Literature DB >> 6972328

Measurement of local cerebral blood flow and metabolism in man with positron emission tomography.

M E Raichle.   

Abstract

Positron emission tomography (PET) is a computer based, nuclear medicine imaging technique that permits the quantitative, in vivo measurement of local tissue concentration or radiopharmaceuticals labeled with positron-emitting radionuclides (i.e., 15O, 13N, 11C, and 18F). These measurements can be made through any desired section of the human brain thus creating, in effect, a quantitative in vivo autoradiogram. Combining this imaging technique with appropriate radiopharmaceuticals and mathematical models for the interpretation of tracer behavior permits the safe measurement of local blood flow and metabolism in humans.

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Year:  1981        PMID： 6972328

Source DB:  PubMed          Journal:  Fed Proc        ISSN： 0014-9446


  6 in total

1.  Decoupling of the brain's default mode network during deep sleep.

Authors:  Silvina G Horovitz; Allen R Braun; Walter S Carr; Dante Picchioni; Thomas J Balkin; Masaki Fukunaga; Jeff H Duyn
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-19       Impact factor: 11.205

2.  Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast.

Authors:  Masaki Fukunaga; Tie-Qiang Li; Peter van Gelderen; Jacco A de Zwart; Karin Shmueli; Bing Yao; Jongho Lee; Dragan Maric; Maria A Aronova; Guofeng Zhang; Richard D Leapman; John F Schenck; Hellmut Merkle; Jeff H Duyn
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-03       Impact factor: 11.205

3.  Noninvasive Measurements of Cerebral Blood Flow, Oxygen Extraction Fraction, and Oxygen Metabolic Index in Human with Inhalation of Air and Carbogen using Magnetic Resonance Imaging.

Authors:  Hongyu An; Souvik Sen; Yasheng Chen; William J Powers; Weili Lin
Journal:  Transl Stroke Res       Date:  2011-12-28       Impact factor: 6.829

4.  Loss of cerebral white matter structural integrity tracks the gray matter metabolic decline in normal aging.

Authors:  P Kochunov; A E Ramage; J L Lancaster; D A Robin; S Narayana; T Coyle; D R Royall; P Fox
Journal:  Neuroimage       Date:  2008-11-25       Impact factor: 6.556

5.  Inverse correspondence between hippocampal perfusion and verbal memory performance in older adults.

Authors:  Swati Rane; Brandon A Ally; Erin Hussey; Tracy Wilson; Tricia Thornton-Wells; John C Gore; Manus J Donahue
Journal:  Hippocampus       Date:  2012-10-26       Impact factor: 3.899

6.  Absolute oxygenation metabolism measurements using magnetic resonance imaging.

Authors:  Hongyu An; Qingwei Liu; Cihat Eldeniz; Weili Lin
Journal:  Open Neuroimag J       Date:  2011-11-04
  6 in total

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