Literature DB >> 6970263

High-performance liquid chromatographic assay for benzocaine and p-aminobenzoic acid including preliminary stability data.

P K Narang, G Bird, W G Crouthamel.   

Abstract

A high-performance liquid chromatographic assay was developed that separates and quantitates benzocaine and its primary degradation product, p-aminobenzoic acid. This method is rapid, sensitive, and specific. Preliminary stability data obtained with this method demonstrate its utility for this purpose.

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Year:  1980        PMID： 6970263     DOI： 10.1002/jps.2600691208

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  4 in total

1.  Stability of benzocaine formulated in commercial oral disintegrating tablet platforms.

Authors:  Melanie Köllmer; Carmen Popescu; Prashanth Manda; Leon Zhou; Richard A Gemeinhart
Journal:  AAPS PharmSciTech       Date:  2013-08-30       Impact factor: 3.246

2.  Butyl-p-aminobenzoate. Preparation, characterization and quality control of a suspension injection for epidural analgesia.

Authors:  R J Grouls; E W Ackerman; E J Machielsen; H H Korsten
Journal:  Pharm Weekbl Sci       Date:  1991-02-22

3.  Bioadhesive films containing benzocaine: correlation between in vitro permeation and in vivo local anesthetic effect.

Authors:  Daniele Ribeiro de Araujo; Cristina Padula; Cíntia Maria Saia Cereda; Giovana Radomille Tófoli; Rui Barbosa Brito; Eneida de Paula; Sara Nicoli; Patrizia Santi
Journal:  Pharm Res       Date:  2010-04-28       Impact factor: 4.200

4.  New spectral resolution techniques for resolving and determining the components in binary fixed-dose combinations.

Authors:  Duaa J Al Zakri; Reem H Obaydo; Amir Alhaj Sakur
Journal:  Heliyon       Date:  2019-10-23
  4 in total

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