Literature DB >> 6969760

Requirement of T cells for the development of spontaneous autoimmune thyroiditis in obese strain (OS) chickens.

L C de Carvalho, G Wick, I M Roitt.   

Abstract

A combination of neonatal thymectomy and intensive treatment with a highly specific turkey anti-chicken T cell serum effectively abrogates the spontaneous development of thyroiditis and thyroglobulin autoantibodies in the Obese strain chicken. Thus, in addition to a restraining influence of suppressor T cells on the disease process indicated by earlier studies, it would appear that T cells also make a positive contribution to pathogenesis.

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Year:  1981        PMID: 6969760

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  6 in total

Review 1.  T cell repertoire and autoimmune diseases.

Authors:  L Imberti; A Sottini; D Primi
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

Review 2.  Pathogenesis of spontaneous autoimmune thyroiditis in Obese strain (OS) chickens.

Authors:  G Wick; R Boyd; K Hála; S Thunold; H Kofler
Journal:  Clin Exp Immunol       Date:  1982-01       Impact factor: 4.330

3.  Autoimmune thyroiditis.

Authors:  M H De Baets
Journal:  Surv Immunol Res       Date:  1983

4.  Rous-associated virus type 7 induces a syndrome in chickens characterized by stunting and obesity.

Authors:  J K Carter; C L Ow; R E Smith
Journal:  Infect Immun       Date:  1983-01       Impact factor: 3.441

Review 5.  Avian models with spontaneous autoimmune diseases.

Authors:  Georg Wick; Leif Andersson; Karel Hala; M Eric Gershwin; Carlo Selmi; Gisela F Erf; Susan J Lamont; Roswitha Sgonc
Journal:  Adv Immunol       Date:  2006       Impact factor: 3.543

6.  Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease.

Authors:  S Sakaguchi; N Sakaguchi
Journal:  J Exp Med       Date:  1990-08-01       Impact factor: 14.307

  6 in total

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