Literature DB >> 6969579

Influence of food on absorption of erythromycin ethyl succinate.

P J Thompson, K R Burgess, G E Marlin.   

Abstract

Erythromycin plasma concentrations were determined in 18 subjects after a single dose (800 mg) of a new formulation of erythromycin ethyl succinate taken immediately before, immediately after, and 1 h after food. Adequate absorption occurred with all treatments, although bioavailability was best when the drug was taken before food. Absorption was delayed by food, with the highest and earliest peak plasma erythromycin levels occurring under fasting conditions.

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Year:  1980        PMID: 6969579      PMCID: PMC284098          DOI: 10.1128/AAC.18.5.829

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  11 in total

1.  Studies on absorption of a newly developed enteric-coated erythromycin base.

Authors:  P J McDonald; L E Mather; M J Story
Journal:  J Clin Pharmacol       Date:  1977-10       Impact factor: 3.126

2.  Erythromycin: clinical review I. Clinical pharmacology.

Authors:  P Nicholas
Journal:  N Y State J Med       Date:  1977-11

3.  A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate.

Authors:  S M Bell
Journal:  Med J Aust       Date:  1971-12-18       Impact factor: 7.738

4.  Micromethod for assaying serum levels of erythromycin.

Authors:  S C Bell; J W Hamman; W E Grundy
Journal:  Appl Microbiol       Date:  1969-01

5.  Use of erythromycin ethyl succinate in allergic children.

Authors:  L V Crawford; J Roane
Journal:  Ann Allergy       Date:  1969-01

6.  Bioavailability of erythromycin stearate: influence of food and fluid volume.

Authors:  P G Welling; H Huang; P F Hewitt; L L Lyons
Journal:  J Pharm Sci       Date:  1978-06       Impact factor: 3.534

7.  Human respiratory tract infections with mycoplasmas and their in vitro susceptibility to tetracyclines and some other antibiotics.

Authors:  P A Mårdh
Journal:  Chemotherapy       Date:  1975       Impact factor: 2.544

8.  The influence of food on the bioavailability of new formulations of erythromycin stearate and base.

Authors:  J Rutland; N Berend; G E Marlin
Journal:  Br J Clin Pharmacol       Date:  1979-10       Impact factor: 4.335

9.  Erythromycin jaundice: diagnosis by an in vitro challenge test.

Authors:  W G Cooksley; L W Powell
Journal:  Aust N Z J Med       Date:  1977-06

10.  Bioavailability of erythromycin ethylsuccinate in pediatric patients.

Authors:  T C Coyne; S Shum; A H Chun; L Jeansonne; H C Shirkey
Journal:  J Clin Pharmacol       Date:  1978-04       Impact factor: 3.126

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  5 in total

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Authors:  Lars E Schmidt; Kim Dalhoff
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 2.  Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part II).

Authors:  P Periti; T Mazzei; E Mini; A Novelli
Journal:  Clin Pharmacokinet       Date:  1989-05       Impact factor: 6.447

3.  Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial.

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Journal:  Clin Drug Investig       Date:  2015-05       Impact factor: 2.859

4.  Pharmacokinetic advantages of erythromycin estolate over ethylsuccinate as determined by high-pressure liquid chromatography.

Authors:  D Croteau; M G Bergeron; M LeBel
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191

5.  Antibiotic therapy for adults with neurosyphilis.

Authors:  Diana Buitrago-Garcia; Arturo J Martí-Carvajal; Adriana Jimenez; Lucieni O Conterno; Rodrigo Pardo
Journal:  Cochrane Database Syst Rev       Date:  2019-05-27
  5 in total

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