| Literature DB >> 6969074 |
Abstract
The PI M phenotype of alpha 1-antitrypsin was classified into six subtypes determined by three alleles: PI*MI, PI*M2 and PI*M3. Phenotypes were classified by isoelectric focusing and their distribution agreed closely with Hardy-Weinberg expectations. The proportion of heterozygotes was 53%, which more than trebles the heterozygosity without subtyping, and is comparable to a recent estimate from U.S. whites.Entities:
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Year: 1980 PMID： 6969074 DOI： 10.1038/icb.1980.41
Source DB: PubMed Journal: Aust J Exp Biol Med Sci ISSN： 0004-945X