Literature DB >> 6968789

Thymoma production of T cell growth factor (Interleukin 2).

J J Farrar, J Fuller-Farrar, P L Simon, M L Hilfiker, B M Stadler, W L Farrar.   

Abstract

Phorbol-12-myristate-13-acetate stimulates a subline of mouse EL-4 thymoma cells to produce, in vitro, in very high titer, T cell growth factor (Interleukin 2, IL 2). The EL-4-derived IL 2 has the same m.w. (30,000) and isoelectric point heterogeneity (pI 3.8-4.4) as the IL 2 produced by Con A-stimulated spleen cells. In addition, the thymoma-derived IL 2 exhibits the same spectrum of biologic activities as has been reported for spleen cell-derived IL 2.

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Year:  1980        PMID： 6968789

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  112 in total

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2.  Nucleotide and deduced amino acid sequence of a murine cDNA clone encoding one member of the hsp65 multigene family.

Authors:  E Lotscher; J P Allison
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3.  Characterization of a newly established feline lymphoma-derived cell line (BKD) lacking T and B cell surface markers.

Authors:  R W Engelman; K Machida; R E Longley; W T Liu; L Q Trang; R A Good; N K Day
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4.  Mina, an Il4 repressor, controls T helper type 2 bias.

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Journal:  Nat Immunol       Date:  2009-06-28       Impact factor: 25.606

5.  Identification of genetic determinants responsible for the rapid immunosuppressive activity and the low leukemogenic potential of a variant of Friend leukemia virus, FIS-2.

Authors:  H Y Dai; G I Troseth; M Gunleksrud; T Bruland; L A Solberg; H Aarset; L I Kristiansen; A Dalen
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6.  Shared promoter elements between a viral superantigen and the major histocompatibility complex class II-associated invariant chain.

Authors:  J Arroyo; E Winchester; B S McLellan; B T Huber
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7.  The T-cell mediated immune response to Schistosoma mansoni. I. Generation of stage-specific, MHC-restricted proliferative T-cell clones to soluble egg antigens.

Authors:  N K Mak; C J Sanderson
Journal:  Immunology       Date:  1985-04       Impact factor: 7.397

8.  Interleukin 2 inhibitor in synovial fluid.

Authors:  P Emery; K C Gentry; A Kelso; I R Mackay
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

9.  Analysis of the cytotoxic effects of light-exposed HEPES-containing culture medium.

Authors:  J S Zigler; J L Lepe-Zuniga; B Vistica; I Gery
Journal:  In Vitro Cell Dev Biol       Date:  1985-05

10.  Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis.

Authors:  K Nakanishi; T R Malek; K A Smith; T Hamaoka; E M Shevach; W E Paul
Journal:  J Exp Med       Date:  1984-12-01       Impact factor: 14.307
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