A proposal for the definition of terms related to locomotion of leukocytes and other cells.

There is currently much confusion of terms relating to locomotion of leukocytes and other cells. Standardized and precise use of terms is, however, indispensable for analysis of the basic mechanisms controlling such locomotion. The present proposal is intended to serve as a basis for a standardized system of reporting locomotor behaviour of leukocytes and other cells and their responses to environmental stimuli. Definitions of the terms random locomotion, directional locomotion, chemotaxis, chemokinesis, and intrinsic locomotor capacity are proposed. Examples are given to demonstrate the application of the terms in the experimental and clinical analysis of cell locomotion.