Literature DB >> 6966945

[Effect of exposure to stress on the role of T- and B-lymphocytes in the response of the hematopoietic system].

P D Gorizontov, M I Fedotova, O I Belousova, R M Khaitov, L I Chermeneva.   

Abstract

Cellular composition of the bone marrow, spleen and peripheral blood was studied after 6-hour immobilization on the back in experiments on 4 groups of (CBAxC57BL)F1 mice with varying degree of T lymphocyte deficiency (thymectomy, sham thymectomy, administration of antilymphocytic serum, B mice). The evidence obtained shows that the "lymphoid peak" recorded in the bone marrow during stress is likely to be formed at the expense of T and B lymphocyte migration from the peripheral lymphoid organs. The data have been also obtained, indicating that T lymphocytes migrating to the bone marrow during the first 6-9 hours after the exposure to stress may participate in granulocytopoiesis activation.

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Year:  1980        PMID: 6966945

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN: 0365-9615


  1 in total

1.  Role of corticosteroids in regulating cell migration during emotional-pain stress.

Authors:  B A Frolov; S N Afonina
Journal:  Neurosci Behav Physiol       Date:  1985 Sep-Oct
  1 in total

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