Literature DB >> 6966477

Complement elevation in spinal cord injury.

J Rebhun, J Botvin.   

Abstract

Laboratory studies revealed an elevated complement in 66% of patients with spinal cord injury. It is postulated that the activated complement may be a component of self-feeding immunological mechanism responsible for the failure of regeneration of a mature mammalian spinal cord. There was no evidence that such an injury had any effect on pre-existing atopy.

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Year:  1980        PMID: 6966477

Source DB:  PubMed          Journal:  Ann Allergy        ISSN: 0003-4738


  6 in total

1.  Targeted modulation of the neuroinflammatory response after spinal cord injury: the ongoing quest for the "holy grail".

Authors:  Philip F Stahel; Michael A Flierl
Journal:  Am J Pathol       Date:  2010-10-15       Impact factor: 4.307

Review 2.  Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury.

Authors:  Timothy J Kopper; John C Gensel
Journal:  J Neurosci Res       Date:  2017-07-11       Impact factor: 4.164

Review 3.  The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration.

Authors:  Jessy John Alexander; Aileen Judith Anderson; Scott Robert Barnum; Beth Stevens; Andrea Joan Tenner
Journal:  J Neurochem       Date:  2008-10-24       Impact factor: 5.372

Review 4.  Aberrant Complement System Activation in Neurological Disorders.

Authors:  Karolina Ziabska; Malgorzata Ziemka-Nalecz; Paulina Pawelec; Joanna Sypecka; Teresa Zalewska
Journal:  Int J Mol Sci       Date:  2021-04-28       Impact factor: 5.923

5.  Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.

Authors:  Chuanliang Zhao; Xin Zhou; Jie Qiu; Danqing Xin; Tingting Li; Xili Chu; Hongtao Yuan; Haifeng Wang; Zhen Wang; Dachuan Wang
Journal:  Drug Des Devel Ther       Date:  2019-10-24       Impact factor: 4.162

6.  Complement Protein C3 Suppresses Axon Growth and Promotes Neuron Loss.

Authors:  Sheri L Peterson; Hal X Nguyen; Oscar A Mendez; Aileen J Anderson
Journal:  Sci Rep       Date:  2017-10-10       Impact factor: 4.379

  6 in total

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