Literature DB >> 6965643

Animal pharmacology of oxapadol (MD 720111), a new non-narcotic analgesic.

G Mocquet, A Coston, M Jalfre.   

Abstract

Oxapadol is a non-narcotic analgesic with an unusual chemical structure. It possesses analgesic activity in 4 species similar to that of other non-narcotic reference analgesics. It also shows antipyretic and antiinflammatory effects and in the analgesic dose range is devoid of undesirable neurological, gastro-intestinal and cardiovascular side-effects.

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Year:  1980        PMID： 6965643     DOI： 10.1007/BF02003996

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.

Authors:  F GUZMAN; C BRAUN; R K LIM; G D POTTER; D W RODGERS
Journal:  Arch Int Pharmacodyn Ther       Date:  1964-06-01

2.  Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.

Authors:  C A WINTER; E A RISLEY; G W NUSS
Journal:  Proc Soc Exp Biol Med       Date:  1962-12

3.  [Importance of certain electrical parameters in the stimulation of the dental pulp of the rabbit. Applications to antipyretics and analgesics].

Authors:  B LAFFARGUE
Journal:  Ann Pharm Fr       Date:  1963-01

4.  A study of pharmacological influences on ultraviolet erythema in guinea pigs.

Authors:  C V WINDER; J WAX; V BURR; M BEEN; C E ROSIERE
Journal:  Arch Int Pharmacodyn Ther       Date:  1958-09-01

5.  A method for measurement of analgesic activity on inflamed tissue.

Authors:  L O RANDALL; J J SELITTO
Journal:  Arch Int Pharmacodyn Ther       Date:  1957-09-01

6.  A method for evaluating both non-narcotic and narcotic analgesics.

Authors:  E SIEGMUND; R CADMUS; G LU
Journal:  Proc Soc Exp Biol Med       Date:  1957 Aug-Sep

7.  The mouse jumping test--a simple screening method to estimate the physical dependence capacity of analgesics.

Authors:  J K Saelens; F R Granat; W K Sawyer
Journal:  Arch Int Pharmacodyn Ther       Date:  1971-04

8.  A modification of the bradykinin-induced writhing test for analgesia.

Authors:  R B Burns; N J Alioto; K E Hurley
Journal:  Arch Int Pharmacodyn Ther       Date:  1968-09

9.  [Action of caffeine on the spontaneous motility of the mouse].

Authors:  J R Boissier; P Simon
Journal:  Arch Int Pharmacodyn Ther       Date:  1965-11

10.  Application of nonparametric procedure for bioassay data to the evaluation of analgesics in man.

Authors:  L M Fuccella; G Corvi; F Gorini; V Mandelli; G Mascellani; F Nobili; S Pedronetto; N Ragni; I Vandelli
Journal:  J Clin Pharmacol       Date:  1977-04       Impact factor: 3.126
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