Literature DB >> 6965301

A PMN-derived factor that enhances DNA-synthesis in PHA or antigen-stimulated lymphocytes.

M Yoshinaga, K Nishime, S Nakamura, F Goto.   

Abstract

The DNA synthesis potentiation of a mouse polymorphonuclear leukocyte (PMN) factor was studied by using phytohemagglutinin (PHA)-stimulated syngeneic thymocytes. The partially purified PMN factor was nonmitogenic and exhibited maximum potentiation of thymocytes when added within 3 hr of PHA stimulation. PHA-stimulated, but not nonstimulated thymocytes absorbed PMN potentiation factor. 125I-labeled factor binding to stimulated thymocytes was observed. Our results suggest that an acceptor site for PMN factor may be generated on the thymocyte surface only after PHA stimulation.

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Year:  1980        PMID： 6965301

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  9 in total

1.  Effects of supernatants and lysates of polymorphonuclear leucocytes: macrophage stimulatory factors.

Authors:  J Bird; Y J Sheng; J P Giroud
Journal:  Br J Exp Pathol       Date:  1984-04

2.  Localized pulmonary neutrophil influx induced by lung lavage in sheep.

Authors:  R A Weiss; A D Chanana; D D Joel
Journal:  Lung       Date:  1983       Impact factor: 2.584

3.  A possible role of PMN in a casein-induced enhancement of PFC response to sheep erythrocytes in mice.

Authors:  S Nakayama; J Rodriguez-Pinzon; S Nakamura; M Yoshinaga
Journal:  Immunology       Date:  1982-04       Impact factor: 7.397

4.  An in vitro effect of an acute non-specific inflammatory serum on rat lymphocytes proliferative response to PHA.

Authors:  Y J Sheng; I Florentin; J Bird; P Michel; A Pompidou; J P Giroud
Journal:  Agents Actions       Date:  1984-06

5.  Human mononuclear cells and neutral proteinases. III. Neutral proteinases and rheumatoid arthritis: monocytes as a source of cathepsin G and proteinase potentiation of IgM rheumatoid factor elaboration.

Authors:  R S Panush
Journal:  Inflammation       Date:  1989-06       Impact factor: 4.092

6.  Effects of supernatants of polymorphonuclear neutrophils recruited by different inflammatory substances on mitogen responses of lymphocytes.

Authors:  M L Rodrick; I B Lamster; S T Sonis; S G Pender; A B Kolodkin; J E Fitzgerald; R E Wilson
Journal:  Inflammation       Date:  1982-03       Impact factor: 4.092

7.  Production of a lymphocyte proliferation potentiating factor by purified polymorphonuclear leucocytes from mice and rabbits.

Authors:  F Goto; S Nakamura; K Goto; M Yoshinaga
Journal:  Immunology       Date:  1984-12       Impact factor: 7.397

8.  Modulation of human mononuclear cell responses by neutrophil-derived factors. II. Partial characterization of a neutrophil-derived lymphocyte-enhancing factor (N-LEF).

Authors:  R S Panush
Journal:  Inflammation       Date:  1983-03       Impact factor: 4.092

9.  Antitumor effect induced by a hot water extract of Chlorella vulgaris (CE): resistance to Meth-A tumor growth mediated by CE-induced polymorphonuclear leukocytes.

Authors:  F Konishi; K Tanaka; K Himeno; K Taniguchi; K Nomoto
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968
  9 in total

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