Literature DB >> 696481

Biochemical study on myelin in adrenoleukodystrophy.

T Miyatake, T Ariga, T Atsumi, Y Komiya.   

Abstract

Two myelin fractions, heavy and light, were isolated from white matter of a patient with adrenoleukodystrophy. Morphologically, heavy myelin fraction showed compact lamellar structures, and light myelin fraction consisted of loose lamellar structures and rod-like clear space. Analytical studies demonstrated that the chemical composition of heavy myelin fraction was almost the same as that of normal myelin and that light myelin fraction consisted mainly of cholesterol. Long chain saturated fatty acids, C25:0 and C26:0, were increased and C24:1 was decreased in sphingoglycolipids of heavy myelin fraction of the patient.

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Year:  1978        PMID: 696481     DOI: 10.1007/978-1-4684-2514-7_43

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

1.  Determination of C20-C30 fatty acids by reversed-phase chromatographic techniques: an efficient method to quantitate minor fatty acids in serum of patients with adrenoleukodystrophy.

Authors:  M Alberghina; A Fiumara; L Pavone; A M Giuffrida
Journal:  Neurochem Res       Date:  1984-12       Impact factor: 3.996

  1 in total

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