Literature DB >> 69623

Chemistry of bleomycin. XVIII. carbon-13 NMR studies.

H Naganawa, Y Muraoka, T Takita, H Umezawa.   

Abstract

During chemical studies of bleomycin, many fragments and derivatives have been isolated and characterized. The 13C-NMR spectra of these compounds were taken and analyzed for structural information, and the complete assignment of the spectra was achieved. The 13C-chemical shift map thus obtained contains information about the structure and conformation and will be useful for studies on the chemistry and biology of bleomycin and related compounds.

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Year:  1977        PMID： 69623     DOI： 10.7164/antibiotics.30.388

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  NC1404, a novel derivative of Bleomycin with modified sugar moiety obtained during the preparation of Boningmycin.

Authors:  Xin Qi; Xinwei Wang; Hao Ren; Feng Zhang; Xiumin Zhang; Ning He; Wenqiang Guo; Ruxian Chen; Yunying Xie; Qiyang He
Journal:  J Antibiot (Tokyo)       Date:  2017-05-31       Impact factor: 2.649

2.  In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway.

Authors:  Ute Galm; Liyan Wang; Evelyn Wendt-Pienkowski; Runying Yang; Wen Liu; Meifeng Tao; Jane M Coughlin; Ben Shen
Journal:  J Biol Chem       Date:  2008-08-12       Impact factor: 5.157

Review 3.  Contributions of NMR to the understanding of the coordination chemistry and DNA interactions of metallo-bleomycins.

Authors:  Teresa Lehmann; Elena Topchiy
Journal:  Molecules       Date:  2013-08-02       Impact factor: 4.411
  3 in total

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