Literature DB >> 69604

Frequency of Ag-stained nucleolus organizer regions in the acrocentric chromosomes of man.

A V Mikelsaar, M Schmid, W Krone, H G Schwarzacher, W Schnedl.   

Abstract

The Ag-stainability of the nucleolus organizer region (NOR) was studied in the acrocentric chromosomes identified by Q-banding of cultured lymphocytes in 51 karyotypically normal persons (31 males and 20 females). A consistent pattern of Ag-positive NORs was found in each individual. Ninety percent of individuals have a model number of 8--10 Ag-positive NORs per cell. The frequency of Ag-positive NORs is similar in all five acrocentrics. A statistically nonsignificant lower frequency is found in chromosome 22. Ag-negative NORs on both homologues were found in four cases. The observed frequency distribution of individuals with homozygous NOR-positive, heterozygous, and homozygous negative acrocentric chromosomes was in accordance with the Hardy-Weinberg law in all five pairs of the acrocentric chromosomes as well as in total. No sex difference was observed on our material.

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Year:  1977        PMID： 69604     DOI： 10.1007/BF00293774

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  7 in total

1.  Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids.

Authors:  O J Miller; D A Miller; V G Dev; R Tantravahi; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

2.  Suppression of human nucleolus organizer activity in mouse-human somatic hybrid cells.

Authors:  D A Miller; V G Dev; R Tantravahi; O J Miller
Journal:  Exp Cell Res       Date:  1976-09       Impact factor: 3.905

3.  An improved technique for selective silver staining of nucleolar organizer regions in human chromosomes.

Authors:  S E Bloom; C Goodpasture
Journal:  Hum Genet       Date:  1976-10-28       Impact factor: 4.132

4.  Differential staining of the satellite regions of human acrocentric chromosomes.

Authors:  W M Howell; T E Denton; J R Diamond
Journal:  Experientia       Date:  1975-02-15

5.  Visualization of nucleolar organizer regions im mammalian chromosomes using silver staining.

Authors:  C Goodpasture; S E Bloom
Journal:  Chromosoma       Date:  1975-11-20       Impact factor: 4.316

6.  Human nucleolar organizer chromosomes: satellite associations.

Authors:  T E Denton; W M Howell; J V Barrett
Journal:  Chromosoma       Date:  1976-03-31       Impact factor: 4.316

7.  Human nucleolus organizers: the satellites or the stalks?

Authors:  C Goodpasture; S E Bloom; T C Hsu; F E Arrighi
Journal:  Am J Hum Genet       Date:  1976-11       Impact factor: 11.025
  7 in total
  34 in total

1.  Transcriptional repression mechanisms of nucleolus organizer regions (NORs) in humans and chimpanzees.

Authors:  Ana Karina Zavala Guillén; Yuriko Hirai; Tetsuya Tanoue; Hirohisa Hirai
Journal:  Chromosome Res       Date:  2004       Impact factor: 5.239

2.  Rapid identification of chromosomes carrying silver-stained nucleolus-organizing regions: application to case of 21/21 Robertsonian translocation.

Authors:  C H Buys; J Osinga; W L Gouw; G J Anders
Journal:  Hum Genet       Date:  1978-10-31       Impact factor: 4.132

3.  Heterogeneities in the distribution of (GACA)n simple repeats in the karyotypes of primates and mouse.

Authors:  I Nanda; C Deubelbeiss; M Guttenbach; J T Epplen; M Schmid
Journal:  Hum Genet       Date:  1990-07       Impact factor: 4.132

4.  Comparison of silver staining of nucleolus organizer regions in human lymphocytes and fibroblasts.

Authors:  A V Mikelsaar; H G Schwarzacher
Journal:  Hum Genet       Date:  1978-06-27       Impact factor: 4.132

5.  Satellite association frequency and number of nucleoli depend on cell cycle duration and NOR-activity. Studies on first, second, and third mitoses of lymphocyte cultures.

Authors:  J Sigmund; H G Schwarzacher; A V Mikelsaar
Journal:  Hum Genet       Date:  1979       Impact factor: 4.132

6.  Age-G staining, a rapid technique for producing combined silver staining and Giemsa banding in mammalian chromosomes.

Authors:  R Czaker; B Mayr
Journal:  Experientia       Date:  1980-05-15

7.  Comparison of acrocentric associations in male and female cells. Relationship to the active nucleolar organizers.

Authors:  H Galperin-Lemaître; L Hens; B Sele
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

8.  Detection of nucleolus organizer regions (NOR) in the chromosomes of the domestic pig (Sus scrofa domestica L.).

Authors:  R Czaker; B Mayr
Journal:  Experientia       Date:  1980-12-15

9.  Familial silver staining patterns of human nucleolus organizer regions (NORs).

Authors:  E F Taylor; P A Martin-DeLeon
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

10.  Heterochromatins and band karyotypes in three species of salmonids.

Authors:  B Mayr; M Kalat; P Rab
Journal:  Theor Appl Genet       Date:  1988-07       Impact factor: 5.699
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