Literature DB >> 6959196

Preliminary studies with citalopram (LU 10-171), a specific 5-HT-reuptake inhibitor, as antidepressant.

M Gastpar, G Gastpar.   

Abstract

1. Ten hospitalized, depressive, female patients above the age of 50 have been treated in a 3 week open trial with citalopram, a specific 5-HT-uptake inhibitor. 2. Six full and two partial responders demonstrate a recovery rate within the well known range for tricyclic antidepressant drugs. 3. Early onset of clinical effect and minimal side effects indicate that citalopram is possible a new effective antidepressant.

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Year:  1982        PMID： 6959196     DOI： 10.1016/s0278-5846(82)80182-6

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN： 0278-5846            Impact factor:   5.067


  8 in total

1.  Kinetics of citalopram in elderly patients.

Authors:  K Fredericson Overø; B Toft; L Christophersen; J P Gylding-Sabroe
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

2.  Comparative animal studies on cardiovascular toxicity of tri- and tetracyclic antidepressants and citalopram; relation to drug plasma levels.

Authors:  V Boeck; A Jørgensen; K Fredricson Overø
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

3.  Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain.

Authors:  Y Chaput; C de Montigny; P Blier
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-08       Impact factor: 3.000

Review 4.  Citalopram. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.

Authors:  R J Milne; K L Goa
Journal:  Drugs       Date:  1991-03       Impact factor: 9.546

5.  Relationship between clinical effects, serum drug concentration and serotonin uptake inhibition in depressed patients treated with citalopram. A double-blind comparison of three dose levels.

Authors:  L Bjerkenstedt; L Flyckt; K F Overø; O Lingjaerde
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

6.  Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram.

Authors:  J Hyttel; K F Overø; J Arnt
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

7.  Clinical and biochemical effects of citalopram, a selective 5-HT reuptake inhibitor--a dose-response study in depressed patients.

Authors:  L Bjerkenstedt; G Edman; L Flyckt; L Hagenfeldt; G Sedvall; F A Wiesel
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

8.  Efficacy and safety of citalopram versus amitriptyline in the treatment of major depression.

Authors:  Anand Mathur; D K Sharma; Ashok Choudhary; Mahendra Jain
Journal:  Indian J Psychiatry       Date:  2005-04       Impact factor: 1.759
  8 in total

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