Literature DB >> 6958348

Low natural killer cell activity in patients with malignant lymphoma.

T Tursz, M C Dokhelar, M Lipinski, J L Amiel.   

Abstract

Natural killer (NK) cell activity was found decreased (mean value: 27.5%) in peripheral blood lymphocytes from 59 untreated patients with malignant lymphoma, when compared to 112 healthy subjects (46.3%) and to 75 cancer patients with nonlymphoid tumors (43.7%) (P less than 0.001). NK cell values were similar in patients with Hodgkin's disease (25.5%) and with non-Hodgkin's lymphoma (28.2%). Decreased NK cell activity was not correlated with age, lymphoma extension or leukocyte counts. A physiological role for NK cells in the immune surveillance against lymphoid neoplasias is discussed.

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Mesh：

Year:  1982        PMID： 6958348     DOI： 10.1002/1097-0142(19821201)50:11<2333::aid-cncr2820501119>3.0.co;2-w

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  14 in total

1.  Bone marrow and peripheral blood natural killer cell activity in lymphomas. Its response to IL-2.

Authors:  L H Caldera; M Leon-Ponte; G Acquatella; N E Bianco; I Blanca
Journal:  Clin Exp Immunol       Date:  1992-04       Impact factor: 4.330

2.  Clinical significance of natural killing activity in patients with advanced lymphoma.

Authors:  K Ono
Journal:  J Clin Immunol       Date:  1998-03       Impact factor: 8.317

Review 3.  Investigation of NK cell function and their modulation in different malignancies.

Authors:  Gordana Konjevic; Vladimir Jurisic; Viktor Jovic; Ana Vuletic; Katarina Mirjacic Martinovic; Sandra Radenkovic; Ivan Spuzic
Journal:  Immunol Res       Date:  2012-04       Impact factor: 2.829

Review 4.  Need for immunologic stimulators during immunosuppression produced by major cancer surgery.

Authors:  W H Cole; L Humphrey
Journal:  Ann Surg       Date:  1985-07       Impact factor: 12.969

5.  Surface markers and cytotoxic activity of blood natural killer cells studied at the single cell level in Hodgkin's disease.

Authors:  E Jezewska; M Björkholm; R Giscombe; G Holm; O Tullgren
Journal:  Clin Exp Immunol       Date:  1985-07       Impact factor: 4.330

6.  Natural killer cell subsets and natural killer-like T-cell populations in benign and neoplastic B-cell proliferations vary based on clinicopathologic features.

Authors:  Sarah E Gibson; Steven H Swerdlow; Raymond E Felgar
Journal:  Hum Pathol       Date:  2011-02-02       Impact factor: 3.466

7.  Natural killing activity in patients with spontaneous regression of malignant lymphoma.

Authors:  K Ono; M Kikuchi; N Funai; M Matsuzaki; Y Shimamoto
Journal:  J Clin Immunol       Date:  1996-11       Impact factor: 8.317

8.  Loss of natural killer activity as an indicator of relapse in acute leukaemia.

Authors:  J A Tratkiewicz; J Szer
Journal:  Clin Exp Immunol       Date:  1990-05       Impact factor: 4.330

9.  Normal natural killer cell activity in Hodgkin's disease patients in remission.

Authors:  D Douer; N Shaked; B Ramot
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

10.  The origin of human NK cells. An ontogenic model derived from studies in patients with immunodeficiencies.

Authors:  H H Peter
Journal:  Blut       Date:  1983-05
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