Literature DB >> 6956921

Efficient photochemical formation of 1 alpha-hydroxyprevitamin D3.

W G Dauben, R B Phillips, P Jefferies.   

Abstract

Control of the band width of the irradiating light between 280 and 310 nm and of the temperature of the reaction permits formation of 1 alpha-hydroxyprevitamin D3 in yields of over 80%, at 40-60% conversion of the 1 alpha-hydroxyprovitamin D3. The procedures developed permit doubling the photochemical yield of the 1 alpha-hydroxyvitamin D3 compounds which are the major circulatory forms of vitamin D3.

Entities:  

Mesh:

Substances:

Year:  1982        PMID: 6956921      PMCID: PMC346842          DOI: 10.1073/pnas.79.16.5115

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  4 in total

Review 1.  Vitamin D and calcium metabolism.

Authors:  H F De Luca; H E Paaren; H K Schnoes
Journal:  Top Curr Chem       Date:  1979

2.  A convenient synthesis of 1 -hydroxy-vitamin D 3 .

Authors:  D H Barton; R H Hesse; M M Pechet; E Rizzardo
Journal:  J Am Chem Soc       Date:  1973-04-18       Impact factor: 15.419

3.  Synthesis and biological activity of 1alpha-hydroxyvitamin D3.

Authors:  C Kaneko; S Yamada; A Sugimoto; Y Eguchi; M Ishikawa
Journal:  Steroids       Date:  1974-01       Impact factor: 2.668

4.  Effect of wavelength on the formation of 1 alpha-hydroxyprevitamin D3 in the ultraviolet irradiation of cholesta-5,7-diene-1 alpha, 3 beta-diol and use of a filter solution in the photochemical reaction in the synthesis of 1 alpha-hydroxyvitamin D3.

Authors:  T Sato; H Yamauchi; Y Ogata; T Kunii; K Kagel; G Katsui; S Toyoshima; M Yasumura; T Kobayashi
Journal:  J Nutr Sci Vitaminol (Tokyo)       Date:  1980       Impact factor: 2.000

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.