| Literature DB >> 6956676 |
M R Geffard, J J Puizillout, M A Delaage.
Abstract
A radioimmunoassay of melatonin using a new iodinated derivative has been developed. Simple chemical treatments have then been designed to convert serotonin, N-acetylserotonin, and 5-methoxytryptamine to melatonin. Thus these four molecules, belonging to the same metabolic pathway, were separately assayed in the same radioimmunological system at the same sensitivity level (0.01 pmol). Some biological results on the circadian variations of melatonin and serotonin in blood, pineal, and miscellaneous brain structures are presented.Entities:
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Year: 1982 PMID： 6956676 DOI： 10.1111/j.1471-4159.1982.tb12565.x
Source DB: PubMed Journal: J Neurochem ISSN： 0022-3042 Impact factor: 5.372