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Literature DB >> 6955783

A scanning calorimetric study of small molecule-lipid bilayer mixtures.

Abstract

The influence of small molecules on the main phase transition of dimyristoyl phosphatidylcholine was observed by high-sensitivity differential scanning calorimetry. The variation with temperature of the excess heat capacity is markedly affected by solid solution formation, which appears to be of frequent occurrence in solutions in lipid bilayers. The experimental results are in some cases in reasonable agreement with ideal solution theory.

Entities: Chemical

Mesh：

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Year: 1982 PMID： 6955783 PMCID： PMC346556 DOI： 10.1073/pnas.79.13.3963

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

22 in total

1. Drug-induced phase change in bilayer as possible mode of action of membrane expanding drugs.

Authors: M K Jain; N Y Wu; L V Wray
Journal: Nature Date: 1975-06-05 Impact factor: 49.962

2. Effects of local anesthetics on membrane properties. I. Changes in the fluidity of phospholipid bilayers.

Authors: D Papahadjopoulos; K Jacobson; G Poste; G Shepherd
Journal: Biochim Biophys Acta Date: 1975-07-18

3. Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes).

Authors: O H Griffith; P J Dehlinger; S P Van
Journal: J Membr Biol Date: 1974 Impact factor: 1.843

4. Interpretation of nonelectrolyte partition coefficients between dimyristoyl lecithin and water.

Authors: J M Diamond; Y Katz
Journal: J Membr Biol Date: 1974 Impact factor: 1.843

5. Thermodynamic constants for nonelectrolyte partition between dimyristoyl lecithin and water.

Authors: Y Katz; J M Diamond
Journal: J Membr Biol Date: 1974 Impact factor: 1.843

6. The effect of anaesthetic-like molecules on the phase transition in smectic mesophases of dipalmitoyllecithin. I. The normal alcohol up to C equals 9 and three inhalation anaesthetics.

Authors: M W Hill
Journal: Biochim Biophys Acta Date: 1974-07-12

7. Nonsolvent water in liposomes.

Authors: Y Katz; J M Diamond
Journal: J Membr Biol Date: 1974 Impact factor: 1.843

8. The membrane concentrations of alcohol anesthetics.

Authors: P Seeman; S Roth; H Schneider
Journal: Biochim Biophys Acta Date: 1971-02-02

9. Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds.

Authors: A W Eliasz; D Chapman; D F Ewing
Journal: Biochim Biophys Acta Date: 1976-10-05

A scanning calorimetric study of small molecule-lipid bilayer mixtures.

1. Drug-induced phase change in bilayer as possible mode of action of membrane expanding drugs.

2. Effects of local anesthetics on membrane properties. I. Changes in the fluidity of phospholipid bilayers.

3. Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes).

4. Interpretation of nonelectrolyte partition coefficients between dimyristoyl lecithin and water.

5. Thermodynamic constants for nonelectrolyte partition between dimyristoyl lecithin and water.

6. The effect of anaesthetic-like molecules on the phase transition in smectic mesophases of dipalmitoyllecithin. I. The normal alcohol up to C equals 9 and three inhalation anaesthetics.

7. Nonsolvent water in liposomes.

8. The membrane concentrations of alcohol anesthetics.

9. Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds.

10. Interactions between anesthetics and lipid mixtures. Normal alcohols.

1. Trans-unsaturated lipid dynamics: modulation of dielaidoylphosphatidylcholine acyl chain motion by ethanol.

2. The effects of water-soluble solutes on the phase transitions of phospholipids.

3. Thermodynamics of phospholipid-sucrose interactions.

4. Effects of cyclosporine A on biomembranes. Vibrational spectroscopic, calorimetric and hemolysis studies.

5. The thermodynamics of simple biomembrane mimetic systems.

6. Tocopheryl Succinate-Induced Structural Changes in DPPC Liposomes: DSC and ANS Fluorescence Studies.

7. Effect of Protocatechuic Acid Ethyl Ester on Biomembrane Models: Multilamellar Vesicles and Monolayers.