Psammoma bodies found in cervicovaginal and/or endometrial smears.

Eight cases of the unusual occurrence of psammoma bodies associated with adenocarcinoma cells in cervicovaginal and/or endometrial smears are presented. Three of the eight cases were advanced ovarian cancers, four were primary endometrial adenocarcinomas, and one was a metastasis of breast cancer to the pouch of Douglas. From our histologic and histochemical observations, psammoma bodies seem to be secretory rather than degenerative in origin.