Literature DB >> 6952138

Walker carcinoma 256: a model for studies on tumor-induced anorexia and cachexia.

A Guaitani, M Recchia, M Carli, M Rocchetti, I Bartosek, S Garattini.   

Abstract

Data on anorexia and cachexia induced by Walker carcinoma 256 in Sprague-Dawley rats were analyzed in order to standardize an experimental model using a statistical (nondeterministical) procedure for assessing the efficacy of potential orexigenic agents. This model was characterized by a mean survival time of 14 +/- 1 days and by food intake and body weight loss starting from day 6 after tumor implantation. The complex course of cachexia was characterized by reduction in the weight of gastrocnemius muscle and epididymal adipose tissue, taken as representative sites of loss of proteins and lipids.

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Year:  1982        PMID： 6952138     DOI： 10.1159/000225631

Source DB:  PubMed          Journal:  Oncology        ISSN： 0030-2414            Impact factor:   2.935


  7 in total

1.  Diminution in adenine nucleotide hydrolysis by platelets and serum from rats submitted to Walker 256 tumour.

Authors:  Andréia Buffon; Vanessa B Ribeiro; Alessandra S Schanoski; João J F Sarkis
Journal:  Mol Cell Biochem       Date:  2006-01       Impact factor: 3.396

Review 2.  Perspectives in the treatment of cancer metastasis.

Authors:  S Garattini
Journal:  Clin Exp Metastasis       Date:  1987 Apr-Jun       Impact factor: 5.150

3.  Pharmacokinetics of fotemustine and BCNU in plasma, liver and tumor tissue of rats bearing two lines of Walker 256 carcinoma.

Authors:  A Guaitani; M Corada; C Lucas; A Lemoine; S Garattini; I Bartosek
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

4.  Chronic exendin-4 treatment prevents the development of cancer cachexia symptoms in male rats bearing the Yoshida sarcoma.

Authors:  Mary Ann Honors; Kimberly P Kinzig
Journal:  Horm Cancer       Date:  2013-10-08       Impact factor: 3.869

5.  Experimental Cancer Cachexia Changes Neuron Numbers and Peptide Levels in the Intestine: Partial Protective Effects after Dietary Supplementation with L-Glutamine.

Authors:  Geraldo E Vicentini; Luciane Fracaro; Sara R G de Souza; Heber A Martins; Flávia A Guarnier; Jacqueline N Zanoni
Journal:  PLoS One       Date:  2016-09-16       Impact factor: 3.240

Review 6.  Cancer cachexia: lessons from Drosophila.

Authors:  Ying Liu; Pedro Saavedra; Norbert Perrimon
Journal:  Dis Model Mech       Date:  2022-03-23       Impact factor: 5.758

7.  Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats.

Authors:  Veridiana Mota Moreira; Claudinéia Conationi da Silva Franco; Kelly Valério Prates; Rodrigo Mello Gomes; Ana Maria Praxedes de Moraes; Tatiane Aparecida Ribeiro; Isabela Peixoto Martins; Carina Previate; Audrei Pavanello; Camila Cristina Ianoni Matiusso; Douglas Lopes Almeida; Flávio Andrade Francisco; Ananda Malta; Laize Peron Tófolo; Sandra da Silva Silveira; Lucas Paulo Jacinto Saavedra; Katia Machado; Paulo Henrique Olivieri da Silva; Gabriel S Fabrício; Kesia Palma-Rigo; Helenir Medri de Souza; Flaviane de Fátima Silva; Giuliana Regina Biazi; Taís Susane Pereira; Elaine Vieira; Rosiane Aparecida Miranda; Júlio Cezar de Oliveira; Luiz Delmar da Costa Lima; Wilson Rinaldi; Maria Ida Ravanelli; Paulo Cezar de Freitas Mathias
Journal:  Front Physiol       Date:  2018-05-08       Impact factor: 4.566
  7 in total

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