| Literature DB >> 6949237 |
M Lehtinen, P Ahrenberg, A Hänninen, E Ikkala, R Lahtinen, A Levanto, I Palva, A Rajamäki, S Rosengard, T Ruutu, S Sarna, O Selroos, T Timonen, E Waris, C Wasastjerna, J Vilpo, P Vuopio.
Abstract
The Finnish Leukaemia Group has carried out a randomized, multicenter trial to study the effect of levamisole on the remission maintained with 6-mercaptopurine and methotrexate in acute myeloid leukaemia in adults. Levamisole was given on 3 consecutive days every 2 weeks. Twenty-five patients received only chemotherapy, while 26 patients received levamisole as well. The patients receiving levamisole showed significantly better remission duration than those given only chemotherapy (P = 0.033, Mantel's summary chi 2-text). There are four long term survivors in the levamisole group versus none in the chemotherapy group. The remissions have lasted 48-75 months.Entities:
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Year: 1982 PMID： 6949237 DOI： 10.1007/978-3-642-81685-7_11
Source DB: PubMed Journal: Recent Results Cancer Res ISSN： 0080-0015