Literature DB >> 6947859

Unusual translocation and chronic myelocytic leukemia: "masked" Philadelphia chromosome (Ph 1).

M Lessard, S Duval, A Fritz.   

Abstract

An unusual Ph 1 translocation in a woman, 65 years old, with chronic myelocytic leukemia is reported. Cytogenetic analysis performed on 150 mitoses examined with Q-, R-, and C-banding revealed evidence for an unusual translocation involving the insertion of a segment of chromosome #9 into chromosome #22, thus masking the presence of a Ph 1. The anomaly can best be described as 46, XX, ins(22;9) (q11;q22 to 34).

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Year:  1981        PMID： 6947859     DOI： 10.1016/0165-4608(81)90017-0

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  3 in total

1.  Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis.

Authors:  Zhenya Tang; Gokce A Toruner; Guilin Tang; C Cameron Yin; Wei Wang; Shimin Hu; Beenu Thakral; Sa A Wang; Roberto N Miranda; Joseph D Khoury; L Jeffrey Medeiros
Journal:  Mod Pathol       Date:  2020-05-13       Impact factor: 7.842

2.  Reciprocal translocation between chromosomes 8 and 9 in atypical chronic myeloid leukaemia.

Authors:  D G Oscier; G J Mufti; A Gardiner; T J Hamblin
Journal:  J Med Genet       Date:  1985-10       Impact factor: 6.318

3.  "Masked" Ph1-chromosome in chronic myelogenous leukaemia (CML).

Authors:  R S Verma; H Dosik
Journal:  Blut       Date:  1985-03
  3 in total

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