Literature DB >> 6947505

The association of goitrous autoimmune thyroiditis with HLA-DR5.

N R Farid, L Sampson, H Moens, J M Barnard.   

Abstract

We found HLA-DR5 to be present among 53% of 40 patients with goitrous autoimmune (Hashimoto's ) thyroiditis compared to 26% of 80 controls. No deviations from those expected in the incidences of HLA-A, B, C antigens were seen. In contrast HLA-DR3 was increased among 50 patients with atrophic thyroiditis (65%) compared to controls (24%). These findings stress the immunogenetic heterogeneity between the goitrous and atrophic varieties of thyroiditis.

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Year:  1981        PMID： 6947505     DOI： 10.1111/j.1399-0039.1981.tb00700.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


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