Literature DB >> 6946252

Efficacy of intratumorally administered mycobacterial cell walls in the treatment of cattle with ocular carcinoma.

S J Kleinschuster, H J Rapp, S B Green, J Bier, K van Kampen.   

Abstract

Individual Hereford cows with naturally occurring ocular squamous cell carcinoma were treated by intralesional injections of mycobacterial cell walls in an oil-in-water emulsion. Six of 23 treated animals were alive (5 free of tumor and 1 with arrested disease) at a minimum of 2.5 years after treatment, as compared to 1 of 18 controls. A necropsy, lymph node metastases were found in most animals with progressive disease. The disease progressed to an advanced stage (which required death of the animals) at a faster rate for control animals than for treated animals.

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Year:  1981        PMID： 6946252

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  6 in total

1.  Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms.

Authors:  M Nelson; D S Nelson; P B Spradbrow; V K Kuchroo; P A Jennings; G J Cianciolo; R Snyderman
Journal:  Clin Exp Immunol       Date:  1985-07       Impact factor: 4.330

2.  Equine sarcoid: BCG immunotherapy compared to cryosurgery in a prospective randomised clinical trial.

Authors:  W R Klein; G E Bras; W Misdorp; P A Steerenberg; W H de Jong; R H Tiesjema; A W Kersjes; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

3.  Immunotherapy of bovine ocular squamous cell carcinoma by repeated intralesional injections of live bacillus Calmette-Guérin (BCG) or BCG cell walls.

Authors:  V P Rutten; W R Klein; W A De Jong; W Misdorp; P A Steerenberg; W H De Jong; W Den Otter; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

4.  Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma.

Authors:  F W Hill; V P Rutten; M H Hoyer; W R Klein; J W Koten; P A Steerenberg; E J Ruitenberg; W Den Otter
Journal:  Cancer Immunol Immunother       Date:  1994-07       Impact factor: 6.968

5.  Clinico-pathological aspects of immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma.

Authors:  W Misdorp; W R Klein; E J Ruitenberg; G Hart; W H de Jong; P A Steerenberg
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968

6.  Experimental screening of BCG preparations produced for cancer immunotherapy: safety and immunostimulating and antitumor activity of four consecutively produced batches.

Authors:  W H de Jong; P A Steerenberg; J G Kreeftenberg; R H Tiesjema; W Kruizinga; L M van Noorle Jansen; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968
  6 in total

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