Literature DB >> 6946247

Comparison of the carcinogenicity of methylazoxymethanol-beta-D-glucosiduronic acid in conventional and germfree Sprague-Dawley rats.

G L Laqueur, H Matsumoto, R S Yamamoto.   

Abstract

Methylazoxymethanol-beta-D-glucosiduronic acid (MAM-GlcUA) was administered to young adult male Sprague-Dawley rats by oral and ip routes. Most neoplasms developed in rats that had received the compound orally. The most prevalent site for the neoplasms was the intestinal tract, predominantly the colon. Comparatively fewer tumors occurred in the liver and kidneys. Germfree rats did not develop tumors when MAM-GlcUA was administered either orally or ip.

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Year:  1981        PMID： 6946247

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  13 in total

1.  Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.

Authors:  Emilie Viennois; Didier Merlin; Andrew T Gewirtz; Benoit Chassaing
Journal:  Cancer Res       Date:  2016-11-07       Impact factor: 12.701

Review 2.  Gut microbiota in liver disease: too much is harmful, nothing at all is not helpful either.

Authors:  Phillipp Hartmann; Huikuan Chu; Yi Duan; Bernd Schnabl
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2019-02-15       Impact factor: 4.052

Review 3.  Glucuronides in the gut: Sugar-driven symbioses between microbe and host.

Authors:  Samuel J Pellock; Matthew R Redinbo
Journal:  J Biol Chem       Date:  2017-04-07       Impact factor: 5.157

Review 4.  The microbiome and lung cancer.

Authors:  Abhiram Maddi; Amarpreet Sabharwal; Timothy Violante; Sunita Manuballa; Robert Genco; Santosh Patnaik; Sai Yendamuri
Journal:  J Thorac Dis       Date:  2019-01       Impact factor: 2.895

5.  Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors.

Authors:  Masayuki Fukata; Yasmin Hernandez; Daisy Conduah; Jason Cohen; Anli Chen; Keith Breglio; Tyralee Goo; David Hsu; Ruliang Xu; Maria T Abreu
Journal:  Inflamm Bowel Dis       Date:  2009-07       Impact factor: 5.325

Review 6.  Role of Toll-like receptors in gastrointestinal malignancies.

Authors:  M Fukata; M T Abreu
Journal:  Oncogene       Date:  2008-01-07       Impact factor: 9.867

Review 7.  Group 3 innate lymphoid cells: regulating host-commensal bacteria interactions in inflammation and cancer.

Authors:  Jeremy Goc; Matthew R Hepworth; Gregory F Sonnenberg
Journal:  Int Immunol       Date:  2015-10-07       Impact factor: 4.823

Review 8.  The microbiome and cancer.

Authors:  Robert F Schwabe; Christian Jobin
Journal:  Nat Rev Cancer       Date:  2013-10-17       Impact factor: 60.716

9.  Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception.

Authors:  Samuel J Pellock; Benjamin C Creekmore; William G Walton; Naimee Mehta; Kristen A Biernat; Andrew P Cesmat; Yamuna Ariyarathna; Zachary D Dunn; Bo Li; Jian Jin; Lindsey I James; Matthew R Redinbo
Journal:  ACS Cent Sci       Date:  2018-07-12       Impact factor: 14.553

10.  Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer.

Authors:  Justin Chau; Meeta Yadav; Ben Liu; Muhammad Furqan; Qun Dai; Shailesh Shahi; Arnav Gupta; Keri Nace Mercer; Evan Eastman; Taher Abu Hejleh; Carlos Chan; George J Weiner; Catherine Cherwin; Sonny T M Lee; Cuncong Zhong; Ashutosh Mangalam; Jun Zhang
Journal:  BMC Cancer       Date:  2021-07-13       Impact factor: 4.430
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