Literature DB >> 6945285

Activity of steroid sulfatase in fibroblasts with numerical and structural X chromosome aberrations.

H H Ropers, B Migl, J Zimmer, M Fraccaro, P P Maraschio, A Westerveld.   

Abstract

In cultured fibroblasts of patients with numerical and structural X chromosome aberrations the activity of steroid sulfatase (STS) is correlated with the number of functional STS gene copies. While normally, this X-linked gene is not inactivated, our data suggest that it may be subject to inactivation when carried on a structurally altered X-chromosome. Similar inactivation patterns have been reported earlier for the Xg locus which, like STS, is located on the distal portion of Xp.

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Year:  1981        PMID： 6945285     DOI： 10.1007/bf00281683

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  16 in total

1.  [The mechanism of gonadal differentiation].

Authors:  U Wolf
Journal:  Bull Schweiz Akad Med Wiss       Date:  1978-11

2.  Abnormal X chromosomes in man: origin, behavior and effects.

Authors:  E Therman; K Patau
Journal:  Humangenetik       Date:  1974

3.  In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain.

Authors:  T R Chen
Journal:  Exp Cell Res       Date:  1977-02       Impact factor: 3.905

4.  X-linked ichthyosis due to steroid-sulphatase deficiency.

Authors:  D Webster; J T France; L J Shapiro; R Weiss
Journal:  Lancet       Date:  1978-01-14       Impact factor: 79.321

5.  Steroid sulfatase activity in cultured fibroblasts of XX males.

Authors:  H H Ropers; B Migl; J Zimmer; C R Müller
Journal:  Cytogenet Cell Genet       Date:  1981

6.  Studies of the biochemical basis of steroid sulphatase deficiency: preliminary evidence suggesting a defect in membrane-enzyme structure.

Authors:  R W McNaught; J T France
Journal:  J Steroid Biochem       Date:  1980-03       Impact factor: 4.292

7.  X-Y translocation in a retarded phenotypic male. Clinical, cytogenetic, biochemical, and serogenetic studies.

Authors:  R Bernstein; J Wagner; J Isdale; G T Nurse; A B Lane; T Jenkins
Journal:  J Med Genet       Date:  1978-12       Impact factor: 6.318

8.  Non-inactivation of an x-chromosome locus in man.

Authors:  L J Shapiro; T Mohandas; R Weiss; G Romeo
Journal:  Science       Date:  1979-06-15       Impact factor: 47.728

9.  Clinical and biochemical investigations on patients with partial deficiency of placental steroid sulfatase.

Authors:  H Hameister; G Wolff; C H Lauritzen; W O Lehmann; A Hauser; H H Ropers
Journal:  Hum Genet       Date:  1979-01-25       Impact factor: 4.132

10.  X-linked steroid sulfatase: evidence for different gene-dosage in males and females.

Authors:  C R Müller; B Migl; H Traupe; H H Ropers
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132
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  23 in total

1.  Short stature in a girl with a terminal Xp deletion distal to DXYS15: localisation of a growth gene(s) in the pseudoautosomal region.

Authors:  T Ogata; P Goodfellow; C Petit; M Aya; N Matsuo
Journal:  J Med Genet       Date:  1992-07       Impact factor: 6.318

2.  Partial lyonisation of steroid sulphatase gene in single hair roots.

Authors:  P J Willems; H W de Bruijn; A Groenhuis; B R Mooyaart; R Berger
Journal:  J Inherit Metab Dis       Date:  1986       Impact factor: 4.982

3.  A family with X-linked ichthyosis and hypogonadism.

Authors:  M G Pike; M Hammerton; J Edge; D J Atherton; D B Grant
Journal:  Eur J Pediatr       Date:  1989-02       Impact factor: 3.183

4.  Linkage of the steroid sulfatase gene to the sex-reversed mutation in the mouse.

Authors:  E A Keitges; D F Schorderet; S M Gartler
Journal:  Genetics       Date:  1987-07       Impact factor: 4.562

5.  Evidence for a dosage effect at the X-linked steroid sulfatase locus in human tissues.

Authors:  P F Chance; S M Gartler
Journal:  Am J Hum Genet       Date:  1983-03       Impact factor: 11.025

6.  Murine arylsulfatase C: evidence for two isozymes.

Authors:  K Nelson; B M Keinanen; W L Daniel
Journal:  Experientia       Date:  1983-07-15

7.  Tissue-specific expression of human arylsulfatase-C isozymes and steroid sulfatase.

Authors:  D G Munroe; P L Chang
Journal:  Am J Hum Genet       Date:  1987-02       Impact factor: 11.025

8.  Steroid sulphatase levels are higher in males than in females of the root vole (Microtus oeconomus). Yet another rodent with an active Y-linked allele?

Authors:  U H Wiberg; K Fredga
Journal:  Hum Genet       Date:  1987-09       Impact factor: 4.132

9.  Steroid sulphatase in man: a non inactivated X-locus with partial gene dosage compensation.

Authors:  G Lykkesfeldt; A E Lykkesfeldt; N E Skakkebaek
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  A comparative study on steroid sulfatase and arylsulfatase C in fibroblast clones from 45,X/47,XXX and 69,XXY.

Authors:  W Vogel; M Grompe; R Storz; S Pentz
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132
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