Literature DB >> 6944538

The crown-gall potato disk bioassay as a primary screen for compounds with antitumor activity.

A G Galsky, R Kozimor, D Piotrowski, R G Powell.   

Abstract

A variety of samples consisting of purified compounds (of various origins) and ethanol extracts from plants were assayed for their activity on the growth and initiation of crown-gall tumors on potato disks. The results demonstrated a high correlation between the ability of these compounds to inhibit the initiation and growth of crown-gall tumors on potato disks and their corresponding activity on the mouse P388 leukemia protocol. Of the 21 compounds tested to date, there were two false-positives and one false-negative.

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Year:  1981        PMID： 6944538

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  5 in total

1.  Polyamines and crown gall tumor growth.

Authors:  J M Kulpa; A G Galsky; P Lipetz; R Stephens
Journal:  Plant Cell Rep       Date:  1985-04       Impact factor: 4.570

2.  Dexibuprofen amide derivatives as potential anticancer agents: synthesis, in silico docking, bioevaluation, and molecular dynamic simulation.

Authors:  Zaman Ashraf; Tariq Mahmood; Mubashir Hassan; Samina Afzal; Hummera Rafique; Khurram Afzal; Jalifah Latip
Journal:  Drug Des Devel Ther       Date:  2019-05-14       Impact factor: 4.162

3.  Antimutagenic, antitumor and estrogen receptor binding activity of the rare plant Shortia galacifolia: An ethnobotanical and chemosystematic approach.

Authors:  Sandra L Gray; Brett R Lackey; Patricia L Tate
Journal:  Avicenna J Phytomed       Date:  2019 Jan-Feb

4.  Synthesis and antitumor activity of substituted succinamides using a potato disc tumor induction assay.

Authors:  Farzin Hadizadeh; Alireza Moradi; Goli Naghibi; Mojgan Vojdani; Javad Behravan; Mohammad Ramezani
Journal:  Int J Biomed Sci       Date:  2007-03

5.  Antitumor properties of two traditional aromatic rice genotypes (Kalijira and Chinigura).

Authors:  Mohammad Abdul Mannan; Tushar Chandra Sarker; Ahmad Humayan Kabir; Mostafizur Rahman; Mohammad Firoz Alam
Journal:  Avicenna J Phytomed       Date:  2014-01
  5 in total

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