Literature DB >> 6944163

Fragile sites in human chromosomes I. The effect of methionine on the Xq fragile site.

P N Howard-Peebles, J C Pryor.   

Abstract

The Xq fragile site found in males having non-specific X-linked mental retardation was studied by varying the chemical and physical parameters of leukocyte cultures. Methionine was shown to be required for marker expression in both medium 199 and MEM. Banding studies indicated that methionine does not function as a stabilizing factor for the fragile site on Xq.

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Year:  1981        PMID： 6944163     DOI： 10.1111/j.1399-0004.1981.tb00703.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  12 in total

1.  The effect of methionine and 5-azacytidine on fragile X expression.

Authors:  M A Abruzzo; M Mayer; P A Jacobs
Journal:  Am J Hum Genet       Date:  1985-01       Impact factor: 11.025

2.  Cytological evidence of defective template in the fragile X chromosome.

Authors:  B Kerem; R Goitein; T Schaap
Journal:  Chromosoma       Date:  1988       Impact factor: 4.316

3.  Folate, methionine, and the fragile X chromosome.

Authors:  J A Reidy
Journal:  Am J Hum Genet       Date:  1984-03       Impact factor: 11.025

4.  Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.

Authors:  J C Mixon; V G Dev
Journal:  Am J Hum Genet       Date:  1983-11       Impact factor: 11.025

5.  Selection and use of a method for the culture of blood leucocytes to reveal the fra(x) site.

Authors:  J S Haslam; R G Chitham; J W Taylor; V Anness
Journal:  J Clin Pathol       Date:  1984-04       Impact factor: 3.411

Review 6.  Nonspecific X-linked mental retardation--a review.

Authors:  G Tariverdian; B Weck
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

7.  Intracellular folate distribution in cultured fibroblasts from patients with the fragile X syndrome.

Authors:  B W Popovich; D S Rosenblatt; B A Cooper; M Vekemans
Journal:  Am J Hum Genet       Date:  1983-09       Impact factor: 11.025

8.  Origin of symmetrical triradial chromosomes in human cells.

Authors:  E M Kuhn; E Therman
Journal:  Chromosoma       Date:  1982       Impact factor: 4.316

9.  X-linked mental retardation with the fragile X. A study of 15 families.

Authors:  J F Mattei; M G Mattei; C Aumeras; M Auger; F Giraud
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

10.  Folic acid and chromosome breakage. II. A methionine effect similar to that in fragile X expression.

Authors:  J A Reidy; A T Chen
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132
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