Literature DB >> 6942432

Galloping induced by pontine tegmentum damage in rats: a form of "Parkinsonian festination" not blocked by haloperidol.

J T Cheng, T Schallert, M De Ryck, P Teitelbaum.   

Abstract

Localized lesions or local applications of gamma-aminobutyric acid (GABA) in the nucleus reticularis tegmenti pontis (NRTP) of rats cause rapidly accelerating forward locomotion. Such "festination" can coexist with blockade of the dopamine system. We suggest that (i) the akinesia produced by dopamine deficiency results at least in part from release of excessive inhibition of locomotion by a neural system whose final common inhibitory path includes the region of the NRTP and (ii) when it occurs in addition to nigrostriatal damage, destruction in the region of the NRTP might be the cause of a form of festination seen in some patients suffering from Parkinsonism.

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Year:  1981        PMID： 6942432      PMCID： PMC319545          DOI： 10.1073/pnas.78.5.3279

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  6-hydroxydopamine and anticholinergic drugs.

Authors:  T Schallert; I Q Whishaw; V D Ramirez; P Teitelbaum
Journal:  Science       Date:  1978-12-15       Impact factor: 47.728

2.  Adipsia and aphagia after 6-hydroxydopamine induced degeneration of the nigro-striatal dopamine system.

Authors:  U Ungerstedt
Journal:  Acta Physiol Scand Suppl       Date:  1971

3.  Nigrostriatal bundle damage and the lateral hypothalamic syndrome.

Authors:  J F Marshall; J S Richardson; P Teitelbaum
Journal:  J Comp Physiol Psychol       Date:  1974-11

4.  Cholinergic-anticholinergic antagonism in parkinsonism.

Authors:  R C Duvoisin
Journal:  Arch Neurol       Date:  1967-08

5.  Neuroleptic and non-neuroleptic catalepsy.

Authors:  B Costall; R J Naylor
Journal:  Arzneimittelforschung       Date:  1973-05

6.  Compulsive, abnormal walking caused by anticholinergics in akinetic, 6-hydroxydopamine-treated rats.

Authors:  T Schallert; I Q Whishaw; V D Ramirez; P Teitelbaum
Journal:  Science       Date:  1978-03-31       Impact factor: 47.728

7.  Parkinsonian akinesia, rigidity and tremor in the monkey. Histopathological and neuropharmacological study.

Authors:  J C Péchadre; L Larochelle; L J Poirier
Journal:  J Neurol Sci       Date:  1976-06       Impact factor: 3.181

8.  Controlled locomotion in the mesencephalic cat: distribution of facilitatory and inhibitory regions within pontine tegmentum.

Authors:  S Mori; H Nishimura; C Kurakami; T Yamamura; M Aoki
Journal:  J Neurophysiol       Date:  1978-11       Impact factor: 2.714

9.  The lateral hypothalamic syndrome: recovery of feeding and drinking after lateral hypothalamic lesions.

Authors:  P TEITELBAUM; A N EPSTEIN
Journal:  Psychol Rev       Date:  1962-03       Impact factor: 8.934

10.  Atropine stereotypy as a behavioral trap: a movement subsystem and electroencephalographic analysis.

Authors:  T Schallert; M De Ryck; P Teitelbaum
Journal:  J Comp Physiol Psychol       Date:  1980-02
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  3 in total

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Journal:  Behav Neurosci       Date:  2015-04       Impact factor: 1.912

Review 2.  Sick-building syndrome fatigue as a possible predation defense.

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Journal:  Integr Physiol Behav Sci       Date:  1995 Jan-Mar

3.  A subcortical inhibitory signal for behavioral arrest in the thalamus.

Authors:  Kristóf Giber; Marco A Diana; Viktor Plattner; Guillaume P Dugué; Hajnalka Bokor; Charly V Rousseau; Zsófia Maglóczky; László Havas; Balázs Hangya; Hendrik Wildner; Hanns Ulrich Zeilhofer; Stéphane Dieudonné; László Acsády
Journal:  Nat Neurosci       Date:  2015-02-23       Impact factor: 24.884
  3 in total

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