| Literature DB >> 6942092 |
Abstract
Irradiated rats were reconstituted with bone marrow from F1 hybrids. Ia antigen of donor-bone marrow origin was detected by an immunoperoxidase technique on cryostat sections and found predominantly in the medulla of rat thymus 2 wk after reconstitution. These Ia-bearing cells increased in number with time after reconstitution, but the Ia on the cortical epithelial cells remained of host origin. The nature of the bone marrow-derived cells and their implication for major histocompatibility complex restriction are discussed.Entities:
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Year: 1981 PMID: 6942092 PMCID: PMC2186196 DOI: 10.1084/jem.153.6.1666
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307