| Literature DB >> 6941955 |
G Cassinelli, F Di Matteo, S Forenza, M C Ripamonti, G Rivola, F Arcamone, A Di Marco, A M Casazza, C Soranzo, G Pratesi.
Abstract
Four glycosides, designated A, B, C and D, are the main components of the anthracycline complex produced by cultures of Micromonospora sp. nov. They were extracted by solvent partition, separated by column chromatography and characterized by chemical and physical methods as 11-deoxy analogues of daunorubicin. Among these new anthracyclines, displaying antibacterial and cytotoxic activity in vitro, 11-deoxydaunorubicin and 11-deoxydoxorubicin are also active against P388 leukemia in mice.Entities:
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Year: 1980 PMID： 6941955 DOI： 10.7164/antibiotics.33.1468
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649