Literature DB >> 6940655

Spontaneous or natural killer cytotoxicity of K562 erythroleukemic cells in normal patients.

J E Nagel, G D Collins, W H Adler.   

Abstract

Peripheral blood mononuclear cells from 200 normal individuals, ages 20 to 95 years, were evaluated for their capability to mediate spontaneous or natural killer (NK) cytotoxicity using the K562 erythroleukemic cells as targets. The results of a 4-hr 51Cr specific release assay demonstrated that the NK activity of normal individuals is independent of age, sex, and smoking habits. Although varying greatly among individuals, the NK activity of 25 persons restudied after a mean 20-month interval remained stable. Deficient NK lytic activity is not characteristic of elderly individuals.

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Mesh：

Year:  1981        PMID： 6940655

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  13 in total

1.  Natural killer cell function is not diminished in the healthy aged and is proportional to the number of NK cells in the peripheral blood.

Authors:  G J Ligthart; H R Schuit; W Hijmans
Journal:  Immunology       Date:  1989-11       Impact factor: 7.397

Review 2.  Natural killer cells: artifact to reality: an odyssey in biology.

Authors:  R K Oldham
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

Review 3.  The biology of the human natural killer cell.

Authors:  J C Roder; H F Pross
Journal:  J Clin Immunol       Date:  1982-10       Impact factor: 8.317

4.  Cigarette smoking is associated with the reduction of lymphokine-activated killer cell and natural killer cell activities.

Authors:  C Inoue; T Takeshita; H Kondo; K Morimoto
Journal:  Environ Health Prev Med       Date:  1996-04       Impact factor: 3.674

5.  Droplet microfluidics for functional temporal analysis and cell recovery on demand using microvalves: application in immunotherapies for cancer.

Authors:  Sagar N Agnihotri; Giovanni Stefano Ugolini; Matthew Ryan Sullivan; Yichao Yang; Agustin De Ganzó; Ji Won Lim; Tania Konry
Journal:  Lab Chip       Date:  2022-08-23       Impact factor: 7.517

6.  Natural cell-mediated cytotoxicity in normal human peripheral blood lymphocytes and its in vitro boosting with BCG.

Authors:  R Mandeville; F M Sombo; N Rocheleau
Journal:  Cancer Immunol Immunother       Date:  1983       Impact factor: 6.968

7.  Abnormal cellular and humoral immunity in childhood acute lymphoblastic leukemia in long-term remission.

Authors:  J Katz; B N Walter; G A Bennetts; M S Cairo
Journal:  West J Med       Date:  1987-02

8.  Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X.

Authors:  Emily Levy; Robert Reger; Filip Segerberg; Melanie Lambert; Caroline Leijonhufvud; Yvonne Baumer; Mattias Carlsten; Richard Childs
Journal:  Front Immunol       Date:  2019-06-05       Impact factor: 7.561

9.  The impact of ageing on natural killer cell function and potential consequences for health in older adults.

Authors:  Jon Hazeldine; Janet M Lord
Journal:  Ageing Res Rev       Date:  2013-05-06       Impact factor: 10.895

10.  Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18.

Authors:  Kevin C Chen; Richard J Stanton; Jareer J Banat; Mark R Wills
Journal:  J Virol       Date:  2016-01-06       Impact factor: 6.549
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