| Literature DB >> 6939878 |
Abstract
Penicillamine-induced systemic lupus erythematosus (SLE) and penicillamine-immune complex nephritis are histologically and serologically distinct. One hundred and twenty patients with Wilson's disease treated with penicillamine have been analyzed. Eight developed the serologic changes of SLE; in 4, it was necessary to discontinue treatment. In addition, 6 patients developed immune complex nephritis, which necessitated discontinuing treatment. All but 1 have since been managed on triethylene tetramine 2HCl (Trien).Entities:
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Year: 1981 PMID: 6939878
Source DB: PubMed Journal: J Rheumatol Suppl ISSN: 0380-0903