Literature DB >> 6938989

Biosynthesis of vitamin B12: nature of the volatile fragment generated during formation of the corrin ring system.

L Mombelli, C Nussbaumer, H Weber, G Müller, D Arigoni.   

Abstract

It is shown with the help of radiolabeled substrates that biological formation of the corrin ligand system of cobyrinic acid is linked with the release of an equivalent of acetic acid from a hydroporphinoid precursor in which the C-20 atom has undergone methylation prior to its excision from the macrocycle.

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Year:  1981        PMID： 6938989      PMCID： PMC318977          DOI： 10.1073/pnas.78.1.11

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  5 in total

1.  Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfers.

Authors:  A R Battersby; E McDonald; R Hollenstein; M Ihara; F Satoh; D C Williams
Journal:  J Chem Soc Perkin 1       Date:  1977

2.  Biosynthesis of vitamin B12: mode of incorporation of factor III into cobyrinic acid.

Authors:  C Nussbaumer; M Imfeld; G Wörner; G Müller; D Arigoni
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

3.  [On the preparation of intermediates in cobyrinic acid biosynthesis by suspensions of Propionibacterium shermanii (author's transl)].

Authors:  K H Bergmann; R Deeg; K D Gneuss; H P Kriemler; G Müller
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1977-10

4.  Ring contraction of hydroporphinoid to corrinoid complexes.

Authors:  V Rasetti; A Pfaltz; C Kratky; A Eschenmoser
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

5.  Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle.

Authors:  A R Battersby; M J Bushell; C Jones; N G Lewis; A Pfenninger
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205
  5 in total
  7 in total

1.  Biosynthesis of vitamin B12: concerning the identity of the two-carbon fragment eliminated during anaerobic formation of cobyrinic acid.

Authors:  J Wang; N J Stolowich; P J Santander; J H Park; A I Scott
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

2.  Biosynthesis of vitamin B12: isolation of precorrin-6x, a metal-free precursor of the corrin macrocycle retaining five S-adenosylmethionine-derived peripheral methyl groups.

Authors:  D Thibaut; L Debussche; F Blanche
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

3.  Biosynthesis of vitamin B12: structure of precorrin-6x octamethyl ester.

Authors:  D Thibaut; F Blanche; L Debussche; F J Leeper; A R Battersby
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

4.  Regulation of cobalamin biosynthetic operons in Salmonella typhimurium.

Authors:  J C Escalante-Semerena; J R Roth
Journal:  J Bacteriol       Date:  1987-05       Impact factor: 3.490

5.  Ring contraction of hydroporphinoid to corrinoid complexes.

Authors:  V Rasetti; A Pfaltz; C Kratky; A Eschenmoser
Journal:  Proc Natl Acad Sci U S A       Date:  1981-01       Impact factor: 11.205

6.  Bactobilin: blue bile pigment isolated from Clostridium tetanomorphum.

Authors:  P J Brumm; J Fried; H C Friedmann
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

7.  Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans.

Authors:  L Debussche; D Thibaut; B Cameron; J Crouzet; F Blanche
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490
  7 in total

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