Prostaglandins in gingiva of patients with periodontal disease.

Prostaglandin E and F were measured simultaneously by radioimmunoassay in extracts of gingiva of patients with chronic periodontal disease. The mean values of PGE and PGF in 27 gingival samples were 42.2 +/- 4.9 and 52.6 +/- 6.8 pmol/gm wet tissue weight, respectively. The correlation coefficient (r) between the two groups of PGs was a positive 0.42, significant at P less than 0.05.