Literature DB >> 6937275

Human osteosarcoma-derived soluble bone morphogenetic protein.

F C Bauer, M R Urist.   

Abstract

A bone morphogenetic protein (BMP) fraction obtained from the organic matrix of dentin is extractable from human osteosarcoma. A fresh en-bloc specimen excised from the femur of a 16-year-old boy was extracted with 4 M guanidine hydrochloride. The GuHCl-soluble, water-insoluble protein fraction induced new bone formation when implanted into the thigh muscles of athymic nude mice.

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Year:  1981        PMID： 6937275

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


  5 in total

Review 1.  Regulation of hematopoiesis.

Authors:  J F Desforges
Journal:  West J Med       Date:  1984-07

2.  The expression of bone morphogenetic proteins in osteosarcoma and its relevance as a prognostic parameter.

Authors:  I Sulzbacher; P Birner; K Trieb; E Pichlbauer; S Lang
Journal:  J Clin Pathol       Date:  2002-05       Impact factor: 3.411

3.  Purification of bovine bone morphogenetic protein by hydroxyapatite chromatography.

Authors:  M R Urist; Y K Huo; A G Brownell; W M Hohl; J Buyske; A Lietze; P Tempst; M Hunkapiller; R J DeLange
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

Review 4.  Bone morphogenetic protein: a review.

Authors:  G Aldinger; G Herr; W Küsswetter; H J Reis; F W Thielemann; U Holz
Journal:  Int Orthop       Date:  1991       Impact factor: 3.075

5.  Bone morphogenetic protein 6 in skeletal metastases from prostate cancer and other common human malignancies.

Authors:  P Autzen; C N Robson; A Bjartell; A J Malcolm; M I Johnson; D E Neal; F C Hamdy
Journal:  Br J Cancer       Date:  1998-11       Impact factor: 7.640
  5 in total

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