Literature DB >> 6936133

Homogeneously staining chromosome regions and double minutes in a mouse adrenocortical tumor cell line.

D L George, U Francke.   

Abstract

We have used a number of banding techniques to analyze the chromosomal content of two sublines of the steroid-secreting mouse adrenocortical tumor cell line Y1. One of the sublines contains marker chromosomes with large "homogeneously staining regions" (HSRs). The other subline contains numerous double minutes, but no HSR. The presence of marker chromosomes shared by both sublines indicates their derivation from a common precursor. Both sublines are karyotypically stable, have similar growth rates, and exhibit positive staining for delta 5, 3 beta-hydroxysteroid dehydrogenase.

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Year:  1980        PMID： 6936133     DOI： 10.1159/000131535

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  11 in total

1.  Increased dihydrofolate reductase, double minutes and increased nucleolar activation in methotrexate-resistant HeLa cells.

Authors:  J G Delinassios; M J Talieri
Journal:  Experientia       Date:  1983-12-15

2.  Amplified DNA sequences in Y1 mouse adrenal tumor cells: association with double minutes and localization to a homogeneously staining chromosomal region.

Authors:  D L George; V E Powers
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

3.  Chromosome analysis of two rat tumor cell lines. Possible role of DMs and HSR in metastasis.

Authors:  H O Werling; S Ghosh; E Spiess
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

4.  MYCN gene amplification. Identification of cell populations containing double minutes and homogeneously staining regions in neuroblastoma tumors.

Authors:  M Yoshimoto; S R Caminada De Toledo; E M Monteiro Caran; M T de Seixas; M L de Martino Lee; S de Campos Vieira Abib; S M Vianna; S T Schettini; J Anderson Duffles Andrade
Journal:  Am J Pathol       Date:  1999-11       Impact factor: 4.307

5.  Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.

Authors:  Clelia Tiziana Storlazzi; Angelo Lonoce; Maria C Guastadisegni; Domenico Trombetta; Pietro D'Addabbo; Giulia Daniele; Alberto L'Abbate; Gemma Macchia; Cecilia Surace; Klaas Kok; Reinhard Ullmann; Stefania Purgato; Orazio Palumbo; Massimo Carella; Peter F Ambros; Mariano Rocchi
Journal:  Genome Res       Date:  2010-07-14       Impact factor: 9.043

6.  Selection of cells with different chromosomal localizations of the amplified c-myc gene during in vivo and in vitro growth of the breast carcinoma cell line SW 613-S.

Authors:  D Cherif; C Lavialle; N Modjtahedi; M Le Coniat; R Berger; O Brison
Journal:  Chromosoma       Date:  1989-01       Impact factor: 4.316

7.  Relevance of c-fos proto-oncogene induction for the steroidogenic response to ACTH, dcAMP and phorbol ester in adrenocortical cells.

Authors:  E Kimura; C K Frigeri; H A Armelin
Journal:  Mol Cell Biochem       Date:  1993-07-07       Impact factor: 3.396

8.  UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells.

Authors:  T D Tlsty; P C Brown; R T Schimke
Journal:  Mol Cell Biol       Date:  1984-06       Impact factor: 4.272

9.  Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-ras gene and localization of homologous sequences to mouse chromosome 6.

Authors:  D L George; A F Scott; B de Martinville; U Francke
Journal:  Nucleic Acids Res       Date:  1984-03-26       Impact factor: 16.971

10.  A cytogenetic characterization comparing a rat 6TG-resistant strain and 6TG-sensitive clones.

Authors:  Y Yongshan; F Shang; L Lianrui
Journal:  Theor Appl Genet       Date:  1987-05       Impact factor: 5.699
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