| Literature DB >> 6933934 |
Abstract
The dynamics of absorption, distribution, biotransformation, and excretion of propoxur in rat was studied. The animals were given single doses of propoxur: a) 5 mg/kg intravenously (i.v.), b) 5 mg/kg 14-C labelled compound (1.5 muCi) intravenously, c) 50 mg/kg orally. The concentrations of propoxur and its metabolite 2-isopropoxyphenol were determined in blood, liver, kidneys, brain and urine. Pharmacokinetic data concerning absorption, distribution and excretion were calculated.Entities:
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Year: 1980 PMID: 6933934 DOI: 10.1007/978-3-642-67729-8_74
Source DB: PubMed Journal: Arch Toxicol Suppl ISSN: 0171-9750