| Literature DB >> 6933927 |
J Kopecký, I Gut, J Nerudová, D Zachardová, V Holeĉek, J Filip.
Abstract
Acrylonitrile (AN) is metabolized by an oxidative pathway via glycidonitrile and glycolaldehyde cyanohydrin to cyanide (CN-), which is transformed to thiocyanate. The major route of AN metabolism (more than 2/3), however, proceeds via cyanoethylation of glutathione, to N-acetyl-S-(2-cyanoethyl)cysteine (AN-mercapturic acid) as a final product.Entities:
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Year: 1980 PMID： 6933927 DOI： 10.1007/978-3-642-67729-8_66
Source DB: PubMed Journal: Arch Toxicol Suppl ISSN： 0171-9750