Literature DB >> 6929700

HLA haplotypes and long survival in childhood acute lymphoblastic leukaemia treated with transfer factor.

M De Bruyère, G Cornu, T Heremans-Bracke, J Malchaire, G Sokal.   

Abstract

Association between HLA haplotypes and long survival was investigated in 116 children with acute lymphoblastic leukaemia. It was found that patients with A2 B12 and/or A2 B40 haplotypes survived longer than patients wtihout these two haplotypes. Since all children were treated with transfer factor obtained from their relatives, it is suggested that children possessing A2 B12 or A2 B40 haplotypes may respond better to this type of immunotherapy.

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Year:  1980        PMID: 6929700     DOI: 10.1111/j.1365-2141.1980.tb01206.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN: 0007-1048            Impact factor:   6.998


  2 in total

1.  Chronic myelocytic leukaemia: HLA association and decreased erythrocyte C3b receptor expression.

Authors:  P Ruuska; S Silvennoinen-Kassinen; T Timonen; A Tiilikainen
Journal:  Clin Exp Immunol       Date:  1985-02       Impact factor: 4.330

2.  HLA-DPβ1 Asp84-Lys69 antigen-binding signature predicts event-free survival in childhood B-cell precursor acute lymphoblastic leukaemia: results from the MRC UKALL XI childhood ALL trial.

Authors:  G M Taylor; R Wade; A Hussain; P Thompson; I Hann; B Gibson; T Eden; S Richards
Journal:  Blood Cancer J       Date:  2012-07-20       Impact factor: 11.037

  2 in total

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