Literature DB >> 6929484

Could poly(A) align the splicing sites of messenger RNA precursors?

M Bina, R J Feldmann, R G Deeley.   

Abstract

In general, poly(A)-mRNA appears to be derived from larger nuclear RNA precursors. The maturation of these precursors involves excision of sequences of variable length from within the molecule and splicing of the remaining structural and coding sequences. The mechanism by which this process occurs is not known. It does not appear to operate solely through the recognition of a defined primary sequence or through the formation of a consistent secondary structure. We propose an alternative model in which poly(A) facilitates the splicing event by promoting the formation of triple-stranded structures within the mRNA precursor.

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Year:  1980        PMID： 6929484      PMCID： PMC348477          DOI： 10.1073/pnas.77.3.1278

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  46 in total

1.  Three-dimensional structure of a transfer rna in two crystal forms.

Authors:  J L Sussman; S Kim
Journal:  Science       Date:  1976-05-28       Impact factor: 47.728

2.  Atomic coordinates and molecular conformation of yeast phenylalanyl tRNA. An independent investigation.

Authors:  C D Stout; H Mizuno; J Rubin; T Brennan; S T Rao; M Sundaralingam
Journal:  Nucleic Acids Res       Date:  1976-04       Impact factor: 16.971

3.  Structure of yeast phenylalanine tRNA at 3 A resolution.

Authors:  J D Robertus; J E Ladner; J T Finch; D Rhodes; R S Brown; B F Clark; A Klug
Journal:  Nature       Date:  1974-08-16       Impact factor: 49.962

4.  Three-dimensional tertiary structure of yeast phenylalanine transfer RNA.

Authors:  S H Kim; F L Suddath; G J Quigley; A McPherson; J L Sussman; A H Wang; N C Seeman; A Rich
Journal:  Science       Date:  1974-08-02       Impact factor: 47.728

5.  Biogenesis and characterization of histone messenger RNA in HeLa cells.

Authors:  M Adesnik; J E Darnell
Journal:  J Mol Biol       Date:  1972-06-28       Impact factor: 5.469

6.  [Associations of poly A and poly U in acid media. Irreversible phenomenon].

Authors:  J Massoulié
Journal:  Eur J Biochem       Date:  1968-02

7.  Heats of the helix-coil transitions of the poly A-poly U complexes.

Authors:  H Krakauer; J M Sturtevant
Journal:  Biopolymers       Date:  1968-04       Impact factor: 2.505

8.  Infrared study of helix strandedness in the poly A-poly U system.

Authors:  H T Miles; J Frazier
Journal:  Biochem Biophys Res Commun       Date:  1964       Impact factor: 3.575

9.  Helix formation between polyribonucleotides and purines, purine nucleosides and nucleotides. II.

Authors:  F B Howard; J Frazier; M F Singer; H T Miles
Journal:  J Mol Biol       Date:  1966-04       Impact factor: 5.469

10.  Structures for the polynucleotide complexes poly(dA) with poly (dT) and poly(dT) with poly(dA) with poly (dT).

Authors:  S Arnott; E Selsing
Journal:  J Mol Biol       Date:  1974-09-15       Impact factor: 5.469
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  5 in total

1.  Differential polyadenylation pattern of ovalbumin precursor RNAs during development.

Authors:  R Messer; H C Schröder; H J Breter; W E Müller
Journal:  Mol Biol Rep       Date:  1986       Impact factor: 2.316

2.  Nucleotide sequence of a ribosomal RNA gene intron from slime mold Physarum polycephalum.

Authors:  H Nomiyama; Y Sakaki; Y Takagi
Journal:  Proc Natl Acad Sci U S A       Date:  1981-03       Impact factor: 11.205

3.  Detection of high levels of polyadenylate-containing RNA in bacteria by the use of a single-step RNA isolation procedure.

Authors:  Y Gopalakrishna; D Langley; N Sarkar
Journal:  Nucleic Acids Res       Date:  1981-07-24       Impact factor: 16.971

4.  Gene and mRNA for precursor polypeptide VI from adenovirus type 2.

Authors:  G Akusjärvi; H Persson
Journal:  J Virol       Date:  1981-05       Impact factor: 5.103

Review 5.  Modulation of poly(A)(+)mRNA-metabolizing and transporting systems under special consideration of microtubule protein and actin.

Authors:  W E Müller; A Bernd; H C Schröder
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396
  5 in total

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