Literature DB >> 6928500

Genetic drift in a stock of laboratory mice.

V E Papaioannou, M F Festing.   

Abstract

Genetic drift in an outbred stock of CFLP mice was monitored for 6 years using genetic polymorphism for glucose phosphate isomerase (GPI) and the shape of the mandible as genetic markers. Statistically significant drift was found in both characters. The cause of this drift was not determined, though it could have arisen as a result of genetic sampling during hysterectomy derivation. The use of inbred strains is recommended on theoretical grounds of long-term genetic constancy is needed.

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Year:  1980        PMID： 6928500     DOI： 10.1258/002367780780943015

Source DB:  PubMed          Journal:  Lab Anim        ISSN： 0023-6772            Impact factor:   2.471


  6 in total

1.  Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research.

Authors:  Victoria S Jensen; Trine Porsgaard; Jens Lykkesfeldt; Henning Hvid
Journal:  Am J Transl Res       Date:  2016-08-15       Impact factor: 4.060

2.  Individual variation in the propensity to attribute incentive salience to a food cue: influence of sex.

Authors:  Kyle K Pitchers; Shelly B Flagel; Elizabeth G O'Donnell; Leah C Solberg Woods; Martin Sarter; Terry E Robinson
Journal:  Behav Brain Res       Date:  2014-10-31       Impact factor: 3.332

Review 3.  Mouse models for radiation-induced cancers.

Authors:  Leena Rivina; Michael J Davoren; Robert H Schiestl
Journal:  Mutagenesis       Date:  2016-05-21       Impact factor: 3.000

4.  Pleiotropic and other genetic effects influencing the activities of brain and liver enzymes in congenic lines of C57BL/6J mice with defined electrophoretic variant markers.

Authors:  R J Feuers; J B Bishop; L J McGarrity; O E Domon; R R Delongchamp; T H Roderick
Journal:  Biochem Genet       Date:  1982-12       Impact factor: 1.890

5.  Variation in the form of Pavlovian conditioned approach behavior among outbred male Sprague-Dawley rats from different vendors and colonies: sign-tracking vs. goal-tracking.

Authors:  Christopher J Fitzpatrick; Shyam Gopalakrishnan; Elizabeth S Cogan; Lindsay M Yager; Paul J Meyer; Vedran Lovic; Benjamin T Saunders; Clarissa C Parker; Natalia M Gonzales; Emmanuel Aryee; Shelly B Flagel; Abraham A Palmer; Terry E Robinson; Jonathan D Morrow
Journal:  PLoS One       Date:  2013-10-01       Impact factor: 3.240

6.  Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies.

Authors:  Thomas D Brekke; Katherine A Steele; John F Mulley
Journal:  G3 (Bethesda)       Date:  2018-02-02       Impact factor: 3.154
  6 in total

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