Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation.

Literature DB >> 6928413

Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation.

Abstract

The satellited-X chromosome previously shown in lymphocyte culture to be associated with certain types of sex-linked mental retardation has, for the first time, been demonstrated in cultured skin fibroblasts and lymphocytes from two affected males and an obligate carrier female. These findings provide a basis for reliable diagnosis of female carriers and for the development of prenatal diagnosis.

Entities: Disease

Mesh：

Substances：
Genetic Markers

Year: 1980 PMID： 6928413 DOI： 10.1007/bf00273509

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

9 in total

1. Effect of 5-bromodeoxyuridine on mamalian chromosomes.

Authors: T C HSU; C E SOMERS
Journal: Proc Natl Acad Sci U S A Date: 1961-03-15 Impact factor: 11.205

2. Fragile sites on human chromosomes: demonstration of their dependence on the type of tissue culture medium.

Authors: G R Sutherland
Journal: Science Date: 1977-07-15 Impact factor: 47.728

3. Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.

Authors: G R Sutherland
Journal: Am J Hum Genet Date: 1979-03 Impact factor: 11.025

4. Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects, and cytogenetics.

Authors: G R Sutherland
Journal: Am J Hum Genet Date: 1979-03 Impact factor: 11.025

5. Banding analysis of abnormal karyotypes in spontaneous abortion.

Authors: T Kajii; K Oama; N Niikawa; A Ferrier; S Avirachan
Journal: Am J Hum Genet Date: 1973-09 Impact factor: 11.025

6. Non-condensation of one segment of a chromosome No. 2 in a male with an otherwise normal karyotype (and severe hypospadias).

Authors: E M Bühler; U Luchsinger; U K Bühler; K Méhes; G R Stalder
Journal: Humangenetik Date: 1970

7. A marker X chromosome.

Authors: H A Lubs
Journal: Am J Hum Genet Date: 1969-05 Impact factor: 11.025

8. Marker X chromosomes, mental retardation and macro-orchidism.

Authors: G Turner; R Till; A Daniel
Journal: N Engl J Med Date: 1978-12-28 Impact factor: 91.245

9. Familial X-linked mental retardation with an X chromosome abnormality.

Authors: J Harvey; C Judge; S Wiener
Journal: J Med Genet Date: 1977-02 Impact factor: 6.318

9 in total

22 in total

1. A comparison of fragile X expression in lymphocyte and lymphoblastoid cultures.

Authors: M A Abruzzo; P A Hunt; M Mayer; P A Jacobs; J C Wang; R W Erbe
Journal: Am J Hum Genet Date: 1986-04 Impact factor: 11.025

2. Inducing fragile sites to express themselves.

Authors: F Hecht; B Kaiser-McCaw
Journal: Am J Hum Genet Date: 1980-07 Impact factor: 11.025

Review 3. Nonspecific X-linked mental retardation--a review.

Authors: G Tariverdian; B Weck
Journal: Hum Genet Date: 1982 Impact factor: 4.132

4. 5-Fluoro-2'-deoxyuridine induction of the fragile site on Xq28 associated with X linked mental retardation.

Authors: N Tommerup; H Poulsen; K Brøndum-Nielsen
Journal: J Med Genet Date: 1981-10 Impact factor: 6.318

Review 5. The fragile X syndrome: the patients and their chromosomes.

Authors: M A De Arce; A Kearns
Journal: J Med Genet Date: 1984-04 Impact factor: 6.318

6. Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28. Results of folic acid treatment on fra(X) expression.

Authors: K B Nielsen; N Tommerup
Journal: Hum Genet Date: 1984 Impact factor: 4.132