Literature DB >> 6928411

Assignment of a structural gene for a fourth human diaphorase (DIA4) to chromosome 16 in man-mouse somatic cell hybrids.

K H Grzeschik.   

Abstract

A diaphorase (DIA4), different from similar enzymes so far described in man, has been detected electrophoretically in human tissues and fibroblasts. The enzyme which is active both with NADH and NADPH was missing in erythrocytes. It was consistently undetectable in part of the diploid fibroblast cultures analyzed. The activity could be separated by Cellogel electrophoresis from rodent diaphorases. In manmouse somatic cell hybrids human DIA4 segregated with chromosome 16. This result indicates that its structural gene is located on this autosome. The enzyme exhibits similarities with a NAD(P)H dehydrogenase (EC 1.6.99.2) described in rat liver.

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Year:  1980        PMID： 6928411     DOI： 10.1007/bf00273494

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  12 in total

1.  THE REDUCED PYRIDINE NUCLEOTIDE DEHYDROGENASES OF HUMAN ERYTHROCYTES.

Authors:  E M SCOTT; I W DUNCAN; V EKSTRAND
Journal:  J Biol Chem       Date:  1965-01       Impact factor: 5.157

2.  Electrophoresis of red cell NADH- and NADPH-diaphorases in normal subjects and patients with congenital methemoglobinemia.

Authors:  J C Kaplan; E Beutler
Journal:  Biochem Biophys Res Commun       Date:  1967-11-30       Impact factor: 3.575

3.  NADPH-flavin reductase in human erythrocytes and the reduction of methemoglobin through flavin by the enzyme.

Authors:  T Yubisui; T Matsuki; K Tanishima; M Takeshita; Y Yoneyama
Journal:  Biochem Biophys Res Commun       Date:  1977-05-09       Impact factor: 3.575

4.  Sperm diaphorase: genetic polymorphism of a sperm-specific enzyme in man.

Authors:  K Caldwell; E T Blake; G F Sensabaugh
Journal:  Science       Date:  1976-03-19       Impact factor: 47.728

5.  Enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--Chinese hamster somatic cell hybrids.

Authors:  P Meera Khan
Journal:  Arch Biochem Biophys       Date:  1971-08       Impact factor: 4.013

6.  An interpretation of human diaphorase isozymes in terms of three gene loci DIA1, DIA2 and DIA3.

Authors:  R A Fisher; Y H Edwards; W Putt; J Potter; D A Hopkinson
Journal:  Ann Hum Genet       Date:  1977-10       Impact factor: 1.670

7.  Some molecular properties of NAD(P)H dehydrogenase from rat liver.

Authors:  R Wallin
Journal:  Biochem J       Date:  1979-07-01       Impact factor: 3.857

8.  Assignment of the DIA1 locus to chromosome 22.

Authors:  R A Fisher; S Povey; M Bobrow; E Solomon; Y Boyd; B Carritt
Journal:  Ann Hum Genet       Date:  1977-10       Impact factor: 1.670

9.  Assignment of NADH-cytochrome b5 reductase (DIA1 locus) to human chromosome 22.

Authors:  C Junien; M Vibert; D Weil; N Van-Cong; J C Kaplan
Journal:  Hum Genet       Date:  1978-06-27       Impact factor: 4.132

10.  Investigations on the polymorphism of sperm diaphorase in man. Evidence for a third common allele, SD.

Authors:  P Kühnl; U Langanke; W Spielmann; M Neubauer
Journal:  Hum Genet       Date:  1977-12-29       Impact factor: 4.132
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  7 in total

1.  Regional mapping of human chromosome 3. Assignment of a glutathione peroxidase-1 gene to 3p13 leads to 3q12.

Authors:  R Johannsmann; B Hellkuhl; K H Grzeschik
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

2.  The isolation of genomic recombinants for the human apolipoprotein B gene and the mapping of three common DNA polymorphisms of the gene--a useful marker for human chromosome 2.

Authors:  N Barni; P J Talmud; P Carlsson; M Azoulay; C Darnfors; D Harding; D Weil; K H Grzeschik; G Bjursell; C Junien
Journal:  Hum Genet       Date:  1986-08       Impact factor: 4.132

3.  Assignment of adenosine deaminase complexing protein (ADCP) gene(s) to human chromosome 2 in rodent-human somatic cell hybrids.

Authors:  E Herbschleb-Voogt; K H Grzeschik; P L Pearson; P Meera Khan
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

4.  A human autosomal phosphoglycerate kinase locus maps near the HLA cluster.

Authors:  P Szabo; K H Grzeschik; M Siniscalco
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

5.  Expression of aromatic polycyclic hydrocarbon-induced monooxygenase (aryl hydrocarbon hydroxylase) in man x mouse hybrids is associated with human chromosome 2.

Authors:  F J Wiebel; P Hlavica; K H Grzeschik
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

6.  Electrophoretic characterization and genetics of human biliverdin reductase (BLVR; EC 1.3.1.24); assignment of BLVR to the p14 leads to cen region of human chromosome 7 in mouse-human somatic cell hybrids.

Authors:  P Meera Khan; L M Wijnen; J T Wijnen; K H Grzeschik
Journal:  Biochem Genet       Date:  1983-02       Impact factor: 1.890

7.  Molecular cloning of a DNA fragment from human chromosome 14(14q11) involved in T-cell malignancies.

Authors:  D Mathieu-Mahul; J F Caubet; A Bernheim; M Mauchauffé; E Palmer; R Berger; C J Larsen
Journal:  EMBO J       Date:  1985-12-16       Impact factor: 11.598
  7 in total

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