Literature DB >> 692714

New structural concepts for narcotic antagonists defined in a 4-phenylpiperidine series.

D M Zimmerman, R Nickander, J S Horng, D T Wong.   

Abstract

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Year:  1978        PMID： 692714     DOI： 10.1038/275332a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  14 in total

Review 1.  Kappa-opioid ligands in the study and treatment of mood disorders.

Authors:  William A Carlezon; Cécile Béguin; Allison T Knoll; Bruce M Cohen
Journal:  Pharmacol Ther       Date:  2009-06-02       Impact factor: 12.310

2.  N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.

Authors:  F Ivy Carroll; Sachin Chaudhari; James B Thomas; S Wayne Mascarella; Kenneth M Gigstad; Jeffrey Deschamps; Hernán A Navarro
Journal:  J Med Chem       Date:  2005-12-29       Impact factor: 7.446

3.  Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonists.

Authors:  Chad M Kormos; Chunyang Jin; Juan Pablo Cueva; Scott P Runyon; James B Thomas; Lawrence E Brieaddy; S Wayne Mascarella; Hernán A Navarro; Brian P Gilmour; F Ivy Carroll
Journal:  J Med Chem       Date:  2013-05-16       Impact factor: 7.446

Review 4.  The discovery and development of the N-substituted trans-3,4-dimethyl-4-(3'-hydroxyphenyl)piperidine class of pure opioid receptor antagonists.

Authors:  F Ivy Carroll; Roland E Dolle
Journal:  ChemMedChem       Date:  2014-06-30       Impact factor: 3.466

5.  1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists.

Authors:  F Ivy Carroll; Juan Pablo Cueva; James B Thomas; S Wayne Mascarella; Scott P Runyon; Hernán A Navarro
Journal:  ACS Med Chem Lett       Date:  2010-10-14       Impact factor: 4.345

6.  Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands.

Authors:  Aaron M Bender; Mary J Clark; Michael P Agius; John R Traynor; Henry I Mosberg
Journal:  Bioorg Med Chem Lett       Date:  2013-12-11       Impact factor: 2.823

Review 7.  Development of κ opioid receptor antagonists.

Authors:  F Ivy Carroll; William A Carlezon
Journal:  J Med Chem       Date:  2013-02-14       Impact factor: 7.446

8.  4β-Methyl-5-(3-hydroxyphenyl)morphan opioid agonist and partial agonist derived from a 4β-methyl-5-(3-hydroxyphenyl)morphan pure antagonist.

Authors:  F Ivy Carroll; Moses G Gichinga; John D Williams; Eyal Vardy; Bryan L Roth; S Wayne Mascarella; James B Thomas; Hernán A Navarro
Journal:  J Med Chem       Date:  2013-11-05       Impact factor: 7.446

9.  Remote Oxidation of Aliphatic C-H Bonds in Nitrogen-Containing Molecules.

Authors:  Jennifer M Howell; Kaibo Feng; Joseph R Clark; Louis J Trzepkowski; M Christina White
Journal:  J Am Chem Soc       Date:  2015-11-13       Impact factor: 15.419

10.  Structure of the human κ-opioid receptor in complex with JDTic.

Authors:  Huixian Wu; Daniel Wacker; Mauro Mileni; Vsevolod Katritch; Gye Won Han; Eyal Vardy; Wei Liu; Aaron A Thompson; Xi-Ping Huang; F Ivy Carroll; S Wayne Mascarella; Richard B Westkaemper; Philip D Mosier; Bryan L Roth; Vadim Cherezov; Raymond C Stevens
Journal:  Nature       Date:  2012-03-21       Impact factor: 49.962
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