Literature DB >> 6920285

Failure of rifampin to eradicate methicillin-resistant Staphylococcus aureus colonization.

H N Canawati, W J Tuddenham, F L Sapico, J Z Montgomerie, G D Aeilts.   

Abstract

Four patients with methicillin-resistant Staphylococcus aureus (MRSA) carriage in one body site each (urine, anterior nares, throat, or wound) received 300 mg of oral rifampin twice daily for ten days. Treatment did not eradicate MRSA carriage in any patient, and three of the posttherapy isolates were highly resistant to the drug. Rifampin by itself does not appear to be an effective drug for the eradication of MRSA carriage.

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Year:  1982        PMID: 6920285

Source DB:  PubMed          Journal:  Clin Ther        ISSN: 0149-2918            Impact factor:   3.393


  3 in total

1.  In vivo verification of in vitro model of antibiotic treatment of device-related infection.

Authors:  J Blaser; P Vergères; A F Widmer; W Zimmerli
Journal:  Antimicrob Agents Chemother       Date:  1995-05       Impact factor: 5.191

2.  Randomized double-blinded trial of rifampin with either novobiocin or trimethoprim-sulfamethoxazole against methicillin-resistant Staphylococcus aureus colonization: prevention of antimicrobial resistance and effect of host factors on outcome.

Authors:  T J Walsh; H C Standiford; A C Reboli; J F John; M E Mulligan; B S Ribner; J Z Montgomerie; M B Goetz; C G Mayhall; D Rimland
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

3.  Eradication of methicillin-resistant Staphylococcus aureus from the lower respiratory tract of patients with cystic fibrosis.

Authors:  D R Burdge; E Nakielna; M Noble
Journal:  Can J Infect Dis       Date:  1995-03
  3 in total

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