Literature DB >> 690635

Uptake of dopamine and 5-hydroxytryptamine by platelets of patients with Parkinsonism.

M J Aminoff, R S Ehsanullah, P Turner.   

Abstract

The uptake of tritiated dopamine and 5-hydroxytryptamine by platelets from 11 patients with Parkinsonism who were not receiving any medication, and from 11 control subjects matched for sex and for age within a decade was compared. No significant differences were found in the uptake of either amine. Our findings, therefore, provide no support for the belief that there is a generalised defect of dopamine systems in Parkinson's disease.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 690635      PMCID： PMC493100          DOI： 10.1136/jnnp.41.7.589

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  10 in total

1.  PLATELET SEQUESTRATION IN MAN. I. METHODS.

Authors:  R H ASTER; J H JANDL
Journal:  J Clin Invest       Date:  1964-05       Impact factor: 14.808

2.  5-Hydroxytryptamine in normal human platelets.

Authors:  R M HARDISTY; R S STACEY
Journal:  J Physiol       Date:  1955-12-29       Impact factor: 5.182

3.  The accumulation and metabolism of dopamine by the human platelet.

Authors:  H M Solomon; N M Spirt; W B Abrams
Journal:  Clin Pharmacol Ther       Date:  1970 Nov-Dec       Impact factor: 6.875

4.  The human platelet as a model for the dopaminergic neuron: kinetic and pharmacologic properties and the role of amine storage granules.

Authors:  S M Stahl; H Y Meltzer
Journal:  Exp Neurol       Date:  1978-03       Impact factor: 5.330

5.  Uptake and efflux of 14-C-dopamine in platelets: evidence for a generalized defect in Parkinson's disease.

Authors:  A Barbeau; G Campanella; R F Butterworth; K Yamada
Journal:  Neurology       Date:  1975-01       Impact factor: 9.910

6.  Accumulation of dopamine by blood platelets from normal subjects and parkinsonian patients under treatment with L-DOPA.

Authors:  D J Boullin; R A O'Brien
Journal:  Br J Pharmacol       Date:  1970-08       Impact factor: 8.739

7.  The uptake of adrenaline and noradrenaline by blood platelets of the pig.

Authors:  G V BORN; O HORNYKIEWICZ; A STAFFORD
Journal:  Br J Pharmacol Chemother       Date:  1958-12

Review 8.  The human platelet. A diagnostic and research tool for the study of biogenic amines in psychiatric and neurologic disorders.

Authors:  S M Stahl
Journal:  Arch Gen Psychiatry       Date:  1977-05

9.  Serotonin content of platelet enriched plasma in Parkinson patients prior and during treatment with L-3,4-dihydroxyphenylalanine (L-DOPA).

Authors:  K Yamaguchi; L Tomasi; L J Cote; R Barrett; M D Yahr
Journal:  Biochem Med       Date:  1972-06

10.  Absorption of serotonin (5-hydroxytryptamine) and histamine by dog platelets.

Authors:  J H HUMPHREY; C C TOH
Journal:  J Physiol       Date:  1954-05-28       Impact factor: 5.182
  10 in total
  1 in total

1.  A Secretory Vesicle Failure in Parkinson's Disease Occurs in Human Platelets.

Authors:  Pablo Montenegro; Mercedes Pueyo; Jesús Norelis Lorenzo; María Dolores Villar-Martinez; Antonio Alayón; Francisco Carrillo; Ricardo Borges
Journal:  Ann Neurol       Date:  2022-03-15       Impact factor: 11.274
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.