| Literature DB >> 6901687 |
E Ohayon, A de Mouzon, G Hauptmann, J Klein, J Ducos.
Abstract
Two hundred and one unrelated French Basque individuals were studied for HLA-A, B, C, DR and Bf polymorphisms. The results show that the Bf S0.7 (Bf S1) variant, which is known to be associated with HLA-Bw21, presents a highly significant linkage disequilibrium with a subtypic specificity, i.e., Bw50 (delta = 0.0123, delta S=100%, P less than 10(-8)). As neither Bf S0.7 variant nor Bw50 antigen is found in Mongoloid populations, it is suggested that in evolutionary terms, the Bf S0.7 mutation is a more recent event than the HLA-Bw21 split.Entities:
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Year: 1980 PMID： 6901687 DOI： 10.1007/bf00291591
Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132