Literature DB >> 6897045

Inactivation of cytochrome P-450 and production of N-alkylated porphyrins caused in isolated hepatocytes by substituted dihydropyridines. Structural requirements for loss of haem and alkylation of the pyrrole nitrogen atom.

F de Matteis, C Hollands, A H Gibbs, N de Sa, M Rizzardini.   

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Year:  1982        PMID: 6897045     DOI: 10.1016/0014-5793(82)81212-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


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  8 in total

Review 1.  Inhibition and induction of cytochrome P450 and the clinical implications.

Authors:  J H Lin; A Y Lu
Journal:  Clin Pharmacokinet       Date:  1998-11       Impact factor: 6.447

2.  Formation of N-methyl protoporphyrin in chemically-induced protoporphyria. Studies with a novel porphyrogenic agent.

Authors:  Y Frater; A Brady; E A Lock; F De Matteis
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

3.  N-alkylation of the haem moiety of cytochrome P-450 caused by substituted dihydropyridines. Preferential attack of different pyrrole nitrogen atoms after induction of various cytochrome P-450 isoenzymes.

Authors:  F De Matteis; A H Gibbs; C Hollands
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857

4.  Labelling in vivo and chirality of griseofulvin-derived N-alkylated protoporphyrins.

Authors:  F De Matteis; A H Gibbs; S R Martin; R L Milek
Journal:  Biochem J       Date:  1991-12-15       Impact factor: 3.857

5.  N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins.

Authors:  F De Matteis; C Harvey; S R Martin
Journal:  Biochem J       Date:  1986-08-15       Impact factor: 3.857

6.  Determination of the structure of an N-substituted protoporphyrin isolated from the livers of griseofulvin-fed mice.

Authors:  R M Bellingham; A H Gibbs; F de Matteis; L Y Lian; G C Roberts
Journal:  Biochem J       Date:  1995-04-15       Impact factor: 3.857

7.  Inhibition of ferrochelatase and accumulation of porphyrins in mouse hepatocyte cultures exposed to porphyrinogenic chemicals.

Authors:  A M Brady; E A Lock
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

Review 8.  The association between chemical-induced porphyria and hepatic cancer.

Authors:  Andrew G Smith; John R Foster
Journal:  Toxicol Res (Camb)       Date:  2018-06-01       Impact factor: 3.524

  8 in total

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